An easy and simple method for the immobilization of dyes through click reactions: activated alkyne, copper not needed

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Date
2024
Author
Sánchez Bodón, Julia
García García, Ane
Díaz Galbarriatu, Maria
Vilas Vilela, José Luis ORCID
Moreno Benitez, María Isabel
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RSC Advances 14(20) : 14289-14295 (2024)
URI
http://hdl.handle.net/10810/68027
Abstract
The copper-free azide–alkyne click reaction has shown to be a successful alternative to immobilize covalently a fluorescente compound onto poly(-L-lactic) acid (PLLA) surfaces. Proceded by basic hydrolysis and amidation reaction, typical surface characterization techniques have validated each functionaliztion step and the success of the conjugation. This method offers a catalyst-free option for various surface conjugations, extremely demanded in biomedical and biosensory fields.
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© 2024 The Author(s). Published by the Royal Society of Chemistry. This article is licensed under a Creative Commons Attribution- Non Commercial 3.0 Unported Licence.
Except where otherwise noted, this item's license is described as © 2024 The Author(s). Published by the Royal Society of Chemistry. This article is licensed under a Creative Commons Attribution- Non Commercial 3.0 Unported Licence.