Click Reactions: An Efficient Tool Towards Biofunctional Materials
Laburpena
In 1987, the European Society for Biomaterials coined the term “biomaterial”, defining it as a non-biological material used in medical devices with the specific purpose of interacting with biological systems. Over time, this definition of biomaterial has evolved, adapting to various contexts. Currently, biomaterials are described as materials that actively interact with biological system to assess, treat, promote healing or even replace any tissue or body function. The main characteristic of a biomaterial is its biocompatibility, which refers to the ability of the material to elicit an appropriate response from the host in a specific situation . Again, the interpretation of biocompatibility varies based on the required performance or function of the material. Chen et al. defined biocompatibility as a factor that can be assessed through parameters such as cell viability, tissue response, tumor formation, genetic integrity, immune reaction, and blood clotting potential . Acknowledging this wide spectrum of considerations, the Food and Drug Administration (FDA) agency has stipulated that to consider a material biocompatible [8], it must not cause harm to the patient.