An overview of the applications of chiral phosphoric acid organocatalysts in enantioselective additions to C=O and C=N bonds
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Date
2022-09-07Author
Del Corte Solaguren-Beascoa, Xabier
Maestro Burzaco, Aitor
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Organic Chemistry Frontiers 9(22) : 6331-6399 (2022)
Abstract
Chiral phosphoric acids (CPAs) have been used as efficient organocatalysts since the first examples were reported 18 years ago by Akiyama and Terada. Although they were originally developed for enantioselective
additions to imines, a wide reaction scope has been demonstrated using this type of catalyst. In this review,
the known applications of CPA for enantioselective additions to C=O and C=N bonds are covered.