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Correlation between biological responses in vitro and in vivo to Ca-doped sol-gel coatings assessed using proteomic analysis
; ; ; ; ; ; ; ; ; Gurruchaga Torrecilla, María Dolores
; Goñi Echave, Isabel María del Coro (Elsevier, 2022-12)
Poor correlation between the results of in vitro testing and the subsequent in vivo experiments hinders the design of biomaterials. Thus, new characterisation methods are needed. This study used proteomic and histological ... -
Desarrollo de fondo transparente para madera curado con UV-LED 395 nm
(2023-10-09)[ES] Esta investigación consistió, principalmente, en el desarrollo y/o adaptación de barnices transparentes para madera 100 % sólidos para curado, mediante lámparas UV-LED de 395 nm, con el objetivo de sustituir las ... -
Desarrollo de recubrimientos para implantes dentales con sales de Ca y Sr, para optimizar los procesos iniciales de regeneración ósea.
(2021-07-07)Uno de los desafíos en la investigación de materiales consiste en desarrollar materiales y/o superficies que incrementen la tasa de éxito de los implantes dentales, pudiendo además recortar los tiempos de recuperación de ... -
Development and characterisation of strontium-doped sol-gel coatings to optimise the initial bone regeneration processes
; ; ; ; ; ; ; Goñi Echave, Isabel María del Coro; Gurruchaga Torrecilla, María Dolores (Elsevier, 2022-12)
Strontium plays an important role in bone regeneration; it promotes the differentiation and maturation of os-teoblasts and inhibits the activity of osteoclasts. Our principal objective in this study was to formulate new ... -
Development of osteoinductive Si-based coatings to improve dental implants' performance
(2015-12-17)Since Professor Brånemark introduced the new concept of osseointegration and the proposal of titanium as the best choice for implants production, many efforts have been done to modify their surface in order to improve the ... -
Influence of Calcium Ion-Modified Implant Surfaces in Protein Adsorption and Implant Integration
; ; ; ; ; ; ; ; Gurruchaga Torrecilla, María Dolores; Goñi Echave, Isabel María del Coro ; ; (Springer, 2021-04-21)
Background Calcium (Ca) is a well-known element in bone metabolism and blood coagulation. Here, we investigate the link between the protein adsorption pattern and the in vivo responses of surfaces modified with calcium ... -
New polymer electrolytes for all-solid-state lithium batteries
(2019-10-18)Los electrolitos poliméricos se presentan como buenos candidatos para reemplazar a los electrolitos líquidos convencionales en dispositivos de almacenamiento de energía. Los polímeros presentan grandes ventajas tales como ... -
Protein adsorption/desorption dynamics on Ca-enriched titanium surfaces: biological implications
Romero Gavilán, Francisco; Cerqueira, Andreia; Anitua Aldekoa, Eduardo; Tejero, Ricardo; ; Martínez Ramos, Cristina; Ozturan, Seda; Izquierdo, Raúl; ; ; Gurruchaga Torrecilla, María Dolores; Goñi Echave, Isabel María del Coro ; Suay, Julio (Springer, 2021-08-27)
Calcium ions are used in the development of biomaterials for the promotion of coagulation, bone regeneration, and implant osseointegration. Upon implantation, the time-dependent release of calcium ions from titanium implant ... -
Proteomic Analysis of Mesenchymal Stem Cells and Monocyte Co-Cultures Exposed to a Bioactive Silica-Based Sol–Gel Coating
; ; ; ; ; Gurruchaga Torrecilla, María Dolores; Goñi Echave, Isabel María del Coro ; ; (American Chemical Society, 2023-05)
New methodologies capable of extensively analyzing the cell-material interactions are necessary to improve current in vitro characterization methods, and proteomics is a viable alternative. Also, many studies are focused ... -
Recubrimientos antibacterianos basados en silicio para implantes dentales
(2016-09-27)El uso de implantes dentales en odontología está tan extendido hoy en día, que ya nadie discute su relevancia. Su tasa de éxitos es elevada (debido al criterio de selección de pacientes), si bien un porcentaje cercano al ... -
Roughness affects the response of human fibroblasts and macrophages to sandblasted abutments
; ; ; ; ; ; ; ; Gurruchaga Torrecilla, María Dolores; Goñi Echave, Isabel María del Coro ; (BMC, 2024)
Background A strong seal of soft-tissue around dental implants is essential to block pathogens from entering the peri-implant interface and prevent infections. Therefore, the integration of soft-tissue poses a challenge ...