BackBrowsing by Author "Bilbao, Jose Ramon"
Now showing items 1-20 of 39
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A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health
Fernández Jiménez, Nora
; ; Cilleros Portet, Ariadna ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Bilbao Catalá, José Ramón (Nature, 2022-11)
Higher maternal pre-pregnancy body mass index (ppBMI) is associated with increased neonatal morbidity, as well as with pregnancy complications and metabolic outcomes in offspring later in life. The placenta is a key organ ... -
A Novel Noninvasive Method Based on Salivary Inflammatory Biomarkers for the Screening of Celiac Disease
Sebastián de la Cruz, Maialen; ; ; ; ; Fernández Jiménez, Nora ; ; ; ; ; ; Irastorza Epelde, Igor ; Bujanda Fernández de Pierola, Luis ; Bilbao Catalá, José Ramón ; (Elsevier, 2021)
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A novel RT-QPCR-based assay for the relative quantification of residue specific m6A RNA methylation
; ; ; ; ; ; Bilbao Catalá, José Ramón (Nature Publishing Group, 2019-12)
N6-methyladenosine (m6A) is the most common and abundant RNA modification. Recent studies have shown its importance in the regulation of several biological processes, including the immune response, and different approaches ... -
A Novel, Noninvasive Method to Diagnose Active Eosinophilic Esophagitis, Combining Clinical Data and Oral Cavity RNA Levels
Sebastián de la Cruz, Maialen; ; Bilbao Catalá, José Ramón ; ; Bujanda Fernández de Pierola, Luis ; (Elsevier, 2024-03)
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A Systematic Two-Sample Mendelian Randomization Analysis Identifies Shared Genetic Origin of Endometriosis and Associated Phenotypes
Garitazelaia González, Aiara; Rueda Martínez, Aintzane; Arauzo, Rebeca; De Miguel, Jokin; Cilleros Portet, Ariadna; Marí Alemany, Sergi; Bilbao Catalá, José Ramón ; Fernández Jiménez, Nora ; García Santisteban, Iraia (MDPI, 2021-01-03)
Endometriosis, one of the most common gynecological disorders, is a complex disease characterized by the growth of endometrial-like tissue in extra-uterine locations and is a cause of pelvic pain and infertility. Evidence ... -
A Two-Sample Mendelian Randomization Analysis Investigates Associations Between Gut Microbiota and Celiac Disease
García Santisteban, Iraia; Cilleros Portet, Ariadna ; Moyua Ormazabal, Elisabet; Kurilshikov, Alexander; Zhernakova, Alexandra; García Etxebarria, Koldo; Fernández Jiménez, Nora ; Bilbao Catalá, José Ramón (MDPI, 2020-05-14)
Celiac disease (CeD) is a complex immune-mediated inflammatory condition triggered by the ingestion of gluten in genetically predisposed individuals. Literature suggests that alterations in gut microbiota composition and ... -
Accuracy in Copy Number Calling by qPCR and PRT : A Matter of DNA
; ; ; ; Irastorza Terradillos, Iñaki Xarles; Castaño González, Luis Antonio ; ; Bilbao Catalá, José Ramón (Public Library of Science, 2011-12-13)
The possible implication of copy number variation (CNV) in the genetic susceptibility to human disease needs to be assessed using robust methods that can be applied at a population scale. In this report, we analyze the ... -
Aldaera ez-kodetzaileak eta epitranskriptomika: eritasun zeliakoarekin asoziatutako eremu baten azterketa funtzionala
(2022-03-11)Eritasun Zeliakoa (EZ) genetikoki sentikorrak diren pertsonetan garatzen den gaixotasun autoimmunekonplexua da. Glutenak erantzun immunea eragiten die eta gaur egun dagoen tratamendu bakarra biziosorako glutenik gabeko ... -
Celiac Diasease-associated lncRNA Named HCG14 Regulates NOD1 Expression in Intestinal Cells
; ; ; ; ; ; Fernández Jiménez, Nora; Irastorza Terradillos, Iñaki Xarles ; Castaño González, Luis Antonio ; Bilbao Catalá, José Ramón (Wiley, 2018-08-01)
Objective: The aim of the study is to identify additional celiac disease associated loci in the major histocompatibility complex (MHC) independent from classical HLA risk alleles (HLA-DR3-DQ2) and to characterize their ... -
Celiac disease in the Mediterranean area
Tucci, Francesca; Astarita, Luca; Abkari, Abdelhak; Abu-Zekry, Mona; Attard, Thomas; Ben Hariz, Mongi; Bilbao Catalá, José Ramón; Boudraa, Ghazalia; Boukthir, Samir; Costa, Stefano; Djurisic, Veselinka; Hugot, Jean-Pierre; Irastorza Terradillos, Iñaki Xarles ; Kansu, Aydan; Kolacek, Sanja; Magazzu, Giuseppe; Micetic-Turk, Dusanka; Misak, Zrinjka; Roma, Eleftheria; Rossi, Pasqualino; Terzic, Selma; Velmishi, Virtut; Arcidiaco, Carmela; Auricchio, Renata; Greco, Luigi; (BioMed Central, 2014-02)
Background: The World Gastroenterology Organization recommends developing national guidelines for the diagnosis of Celiac Disease (CD): hence a profile of the diagnosis of CD in each country is required. We aim to describe ... -
Clinical and molecular characterization of DSD patients: Impact of Next Generation Sequencing in diagnosis
(2020-07-10)Disorders of sex development (DSD) encompass a high heterogeneous range of conditionsin which the optimal clinical management of the individuals comprise clinical description, biochemicaltesting and genetic analysis. With ... -
Combined Analysis of Methylation and Gene Expression Profiles in Separate Compartments of Small Bowel Mucosa Identified Celiac Disease Patients' Signatures
Cielo, D.; Galatola, M.; Fernández Jiménez, Nora; De Leo, L.; García Etxebarria, Koldo; Loganes, C.; Tommasini, A.; Not, T.; Auricchio, Renata; Greco, Luigi; Bilbao Catalá, José Ramón (Nature Publishing Group, 2019-07-10)
By GWAS studies on celiac disease, gene expression was studied at the level of the whole intestinal mucosa, composed by two different compartments: epithelium and lamina propria. Our aim is to analyse the gene-expression ... -
Detection of Atomic Scale Changes in the Free Volume Void Size of Three-Dimensional Colorectal Cancer Cell Culture Using Positron Annihilation Lifetime Spectroscopy
Axpe Iza, Eneko; López Euba, Tamara; Castellanos Rubio, Ainara; Mérida Sanz, David; ; Plaza-Izurieta, Leticia; Fernández-Jiménez, Nora; Plazaola Muguruza, Fernando; Bilbao Catalá, José Ramón (Public Library of Science, 2014-01-02)
Positron annihilation lifetime spectroscopy (PALS) provides a direct measurement of the free volume void sizes in polymers and biological systems. This free volume is critical in explaining and understanding physical and ... -
Endometriosia eta ezaugarri antropometriko eta menstrualak: erlazio genetiko kausalen bila : bi lagineko ausazkotze mendeldar analisia
(2021-12-21)[EU]Endometriosia kausa ezezaguneko gaitz kroniko eta multisistemikoa da, funtzionala den endometrio-ehuna utero-barrunbetik kanpo haztean agertzen dena, besteak beste pelbiseko mina eta antzutasuna eraginez. Ugaltze-adinean ... -
Functional implication of gwas candidate genes in celiac disease pathogenesis
(2016-09-09)La enfermedad celíaca (EC) es una enfermedad autoinmune que se desarrolla en personas con susceptibilidad genética. En los últimos años se han realizado diversos estudios de asociación genómica, en los que se han identificado ... -
Functional studies of tight junction genes in celiac disease
(2017-10-27)La enfermedad celíaca (EC) es una enfermedad autoinmune que se desarrolla en personas con susceptibilidad genética. Durante la patogenia, se observa un aumento de la permeabilidad intestinal debido a una disrupción funcional ... -
Gen LPP : Avances en el conocimiento de uno de los genes candidato de la enfermedad celíaca
Peñalver González, Beatriz (2016-04-28)
[ES] La enfermedad celíaca (EC) es una enteropatía autoinmune de predisposición genética, producida por la ingestión en la dieta de péptidos derivados de cereales como el trigo o la cebada. Aunque se creía que afectaba ... -
Genetic Contribution of Endometriosis to the Risk of Developing Hormone-Related Cancers
Rueda Martínez, Aintzane; Garitazelaia González, Aiara; Cilleros Portet, Ariadna; Marí Alemany, Sergi; Arauzo, Rebeca; De Miguel, Jokin; González García, Bárbara P.; Fernández Jiménez, Nora ; Bilbao Catalá, José Ramón ; García Santisteban, Iraia (MDPI, 2021-06-04)
Endometriosis is a common gynecological disorder that has been associated with endometrial, breast and epithelial ovarian cancers in epidemiological studies. Since complex diseases are a result of multiple environmental ... -
Gluten-induced RNA methylation changes regulate intestinal inflammation via allele-specific XPO1 translation in epithelial cells
Olazagoitia Garmendia, Ane; Zhang, Linda; Mera, Paula; Godbout, Julie K.; Sebastián de la Cruz, Maialen; García Santisteban, Iraia ; Mendoza Gómez, Luis Manuel; Huerta Madrigal, Alain; Irastorza Terradillos, Iñaki Xarles ; Bhagat, Govind; Green, Peter H.; Herrero, Laura; Serra, Dolors; Rodríguez Pérez, José Antonio ; Verdú, Elena F.; He, Chuan; Bilbao Catalá, José Ramón ; Castellanos Rubio, Ainara (BMJ, 2022-01)
[EN] Objectives Coeliac disease (CD) is a complex autoimmune disorder that develops in genetically susceptible individuals. Dietary gluten triggers an immune response for which the only available treatment so far is a ... -
Highly Reproducible Hyperthermia Response in Water, Agar, and Cellular Environment by Discretely PEGylated Magnetite Nanoparticles
; ; ; ; Gil de Muro Zabala, Izaskun; ; Bilbao Catalá, José Ramón ; ; Plazaola Muguruza, Fernando ; Orue Goikuria, Iñaki ; ; (ACS American Chemical Society Publications, 2020-05-28)
Local heat generation from magnetic nanoparticles(MNPs) exposed to alternating magneticfields can revolutionizecancer treatment. However, the application of MNPs as anticanceragents is limited by serious drawbacks. Foremost ...