Browsing by Author "Barrio Beraza, Irantzu"
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Age or lifestyle-induced accumulation of genotoxicity is associated with a length-dependent decrease in gene expression
DNA damage has long been advocated as a molecular driver of aging. DNA damage occurs in a stochastic manner, and is therefore more likely to accumulate in longer genes. The length-dependent accumulation of transcription-blocking ... -
Análisis de modelos estadísticos para estudios de asociación del genoma completo
Gorostiza López de Subijana, Ania (2017-01-09)En este trabajo se introducen técnicas estadísticas que permiten abordar los estudios de asociación del genoma completo. En concreto, se extiende el modelo logístico mediante las regresiones "Ridge", "Lasso" y "Elastic Net". -
Aplicación de metodología estadística para predecir la mortalidad de pacientes con neumonía
Ansola Marlasca, Laura (2016-04-27)[es]Con esta memoria se pretende crear una herramienta de trabajo que ayude a los médicos a clasificar a los pacientes que padecen neumonía en distintos grupos de riesgo dependiendo de su gravedad. Para ello, hemos estudiado ... -
Clinical prediction rules for adverse evolution in patients with COVID-19 by the Omicron variant
Barrio Beraza, Irantzu; COVID-Health Basque Country Research Group (Elsevier, 2023-05)Objective We identify factors related to SARS-CoV-2 infection linked to hospitalization, ICU admission, and mortality and develop clinical prediction rules. Methods Retrospective cohort study of 380,081 patients ... -
Denbora-menpeko aldagaien modelizazioa eta haien diskriminazio-gaitasunaren ebaluazioa biziraupen ereduetan
Enríquez Yurrebaso, Antia (2024-05-10)[EU] Gaur egun, erabakiak hartzeko eredu aurresaleen erabilera gero eta indar handiagoa hartzen ari da. Ikerketa baten interesa gertaera jakin bat eman arte igarotako denbora iragartzean oinarritzen denean, biziraupen ... -
Development and validation of prediction models for complex sampling data
Iparragirre Letamendi, Amaia (2024-03-08)Complex survey data are becoming increasingly well-known among researchers from different fields,including social and health sciences. This type of data is obtained by sampling the target populationthrough a complex sampling ... -
Eredu aurresaleen balidazio tekniken konparaketa eta inplementazioa
Gaur egun, eredu aurresaleak gero eta indar handiagoa hartzen ari dira. Etorkizuneko egoerak aurresan ahal izateko erabiltzen dira, eta adituei egoera horiek kontuan izanda, hartu beharreko neurriak hartzen ... -
Eredu aurresaleetako aldagai jarraituen kategorizaziorik hoberena lortzeko metodologia proposamena: aplikazio zehatza medikuntzan
Barrio Beraza, Irantzu; Arostegui Madariaga, Inmaculada; García Gutiérrez, Susana (Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2014)
Medikuntzan parametro kliniko asko kategorizatzen dira erabaki prozesuak errazteko. Areago arau aurresale klinikoen garapenean ohiko teknika bat da aldagaien kategorizazio hau. Aldagai aurresale bat kategorizatzerakoan ... -
Erregresio logistikoa eta mozketa puntuak: bihotz-gutxiegitasunaren hilkortasunaren azterketa
Murua Etxeberria, Maialen (2015-04-01)Bihotz gutxiegitasun desorekatu larria duten pazienteetan hilkortasunaren eta NT-pro-BNP parametro klinikoaren arteko erlazioa aztertu nahi da. Helburua NT-pro-BNP-ren mozketa puntua kalkulatzea delarik. Horretarako ... -
Five-year follow-up mortality prognostic index for colorectal patients
Orive Calzada, Miren; Barrio Beraza, Irantzu; Lázaro Aramburu, Santiago; González, Nerea; Baré Mañas, Marisa; Fernández de Larrea, Nerea; Redondo, Maximino; Cortajarena, Sarai; Bilbao, Amaia; Aguirre, Urko; Sarasqueta Eizaguirre, Cristina; Quintana López, José María; REDISSEC-CARESS CCR Group (Springer, 2023-03)Purpose To identify 5-year survival prognostic variables in patients with colorectal cancer (CRC) and to propose a survival prognostic score that also takes into account changes over time in the patient’s health-related ... -
Genetic Variants and Hamstring Injury in Soccer: An Association and Validation Study
Larruskain Zabala, Jon; Celorrio Herrera, David; Barrio Beraza, Irantzu; Odriozola Martínez, Adrián; Gil Orozko, Susana María; Fernandez-Lopez, Juan R; Nozal, Raul; Ortuzar Pérez, Isusko; Lekue Gallano, José Antonio
; Aznar, José M. (American College of Sports Medicine, 2018-02)
Purpose: This study aimed to investigate the association of candidate single nucleotide polymorphisms (SNP) with noncontact hamstring muscle injuries in elite soccer players and to create and validate a model to assess the ... -
Hosmer-Lemeshow testean erabilitako talde-kopuruaren azterketa simulazioen bidez
Moreno Oya, Ane (2022-12-20)[EU] Egun, Hosmer-Lemeshow (HL) testa erregresio logistikoko ereduen doikuntza-egokitasuna neurtzeko maiz erabiltzen den tresna da. Ordea, lagin tamainarekin lotuta dauden hainbat eragozpen ditu eta, hori dela eta, azken ... -
Hosmer-Lemeshow testean erabilitako talde-kopuruaren azterketa simulazioen bidez
Moreno Oya, Ane; Barrio Beraza, Irantzu (Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2024)Egun, Hosmer-Lemeshow (HL) testa erregresio logistikoko ereduen doikuntza-egokitasuna neurtzeko maiz erabiltzen den hipotesi-kontrastea da. Ordea, lagin tamainarekin lotuta dauden hainbat eragozpen ditu eta, hori dela eta, ... -
Komunikabideen audientzia ikerkuntzarako metodologia berriak esploratzen: datuen fusioa oinarri duen azterketa aplikatua
Burreso Pardo, Naroa; Amezaga Albizu, Josu; Mimenza Castillo, Libe
; Arana Arrieta, Edorta
; Barrio Beraza, Irantzu (Eusko Jaurlaritzaren Argitalpen Zerbitzu Nagusia. Servicio Central de Publicaciones del Gobierno Vasco., 2023)
[EU] Lan hau Eusko Jaurlaritzako Prospekzio Soziologikoen Kabineteak eta Soziologia eta Zientzia Politikoko Euskal Elkarteak deitutako Jose Ignacio Ruiz Olabuenaga II. Ikerketa Beka deialdiari esker garatutako proiektuaren ... -
Lipidomics signature in post-COVID patient sera and its influence on the prolonged inflammatory response
Fernández Garrido, Pablo; Castillo Peinado, Laura de los Santos; Priego Capote, Feliciano; Barrio Beraza, Irantzu; Piñeiro Guillén, Ángel; Domínguez Santalla, María Jesús; Rodríguez Ruíz, Emilio; García Fandiño, Rebeca (Elsevier, 2024-04)Background The ongoing issues with post-COVID conditions (PCC), where symptoms persist long after the initial infection, highlight the need for research into blood lipid changes in these patients. While most studies ... -
Machine learning-based model for prediction of clinical deterioration in hospitalized patients by COVID 19
García Gutiérrez, Susana; Esteban, Cristóbal; Lafuente Guerrero, Iratxe; Barrio Beraza, Irantzu; Quirós, Raúl; Quintana López, José María; Uranga Echeverría, Ane; COVID-REDISSEC Working Group (Nature Research, 2022)[EN] Despite the publication of great number of tools to aid decisions in COVID-19 patients, there is a lack of good instruments to predict clinical deterioration. COVID19-Osakidetza is a prospective cohort study recruiting ... -
Predictive score for mortality in patients with COPD exacerbations attending hospital emergency departments
Quintana López, José María; Esteban, Cristóbal; Unzurrunzaga, Anette; Garcia-Gutierrez, Susana; González, Nerea; Barrio Beraza, Irantzu; Arostegui Madariaga, Inmaculada; Lafuente Guerrero, Iratxe; Baré Mañas, Marisa; Fernandez-de-Larrea, Nerea; Vidal, Silvia (Biomed Central, 2014-04-23)
Background: Limited information is available about predictors of short-term outcomes in patients with exacerbation of chronic obstructive pulmonary disease (eCOPD) attending an emergency department (ED). Such information ... -
Proposal and validation of methodologies for the categorisation of continuous variables in the development of prediction models
Barrio Beraza, Irantzu (2015-10-20)Prediction models are currently relevant in a number of fieelds such as physics, meteorology, finance or medicine, among others. In the medical field, prediction models are gaining importance as a support for decision-making ... -
Relevance of comorbidities for main outcomes during different periods of the COVID-19 pandemic
Barrio Beraza, Irantzu; COVID-Health Basque Country Research Group (Wiley, 2024-01)Background Throughout the evolution of the COVID-19 pandemic, the severity of the disease has varied. The aim of this study was to determine how patients' comorbidities affected and were related to, different outcomes ... -
The IRYSS-COPD appropriateness study: objectives, methodology, and description of the prospective cohort
Quintana López, José María; Esteban, Cristóbal; Barrio Beraza, Irantzu; García Gutiérrez, Susana; González, Nerea; Arostegui Madariaga, Inmaculada; Lafuente Guerrero, Iratxe; Baré Mañas, Marisa; Blasco, Juan Antonio; Vidal, Silvia; IRYSS-COPD Group (BioMed Central, 2011-11)
Background: Patients with chronic obstructive pulmonary disease (COPD) often experience exacerbations of the disease that require hospitalization. Current guidelines offer little guidance for identifying patients whose ...