Now showing items 1-8 of 8

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      Endocannabinoid long-term depression revealed at medial perforant path excitatory synapses in the dentate gyrus 

      Peñasco Iglesias, Sara; Rico Barrio, Irantzu; Puente Bustinza, Nagore ORCID; Gómez Urquijo, Sonia María ORCID; Fontaine, Christine J.; Egaña Huguet, Jon; Achicallende Urcaregui, Svein ORCID; Ramos Uriarte, Almudena ORCID; Reguero Acebal, Leire ORCID; Elezgarai Gabantxo, Izaskun ORCID; Nahirney, Patrick C.; Christie, Brian R.; Grandes Moreno, Pedro Rolando ORCID (Elsevier, 2019-04-22)
      The endocannabinoid system modulates synaptic plasticity in the hippocampus, but a link between long-term synaptic plasticity and the type 1 cannabinoid (CB1) receptor at medial perforant path (MPP) synapses remains elusive. ...
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      Endokannabinoide sistemaren parte-hartzea arratoien garuntxoaren jaio osteko garapenean 

      Buceta Salazar, Ianire ORCID; Rico Barrio, Irantzu; Egaña Huguet, Jon; Achicallende Urcaregui, Svein ORCID; Terradillos Irastorza, Itziar ORCID; Puente Bustinza, Nagore ORCID; Reguero Acebal, Leire ORCID; Royo, Naiara; Bonilla del Río, Itziar; Medrano, Aitor; Mendizabal Zubiaga, Juan Luis ORCID; Gómez Urquijo, Sonia María ORCID; Ramos, Almudena; Gerrikagoitia Marina, Inmaculada ORCID; Grandes Moreno, Pedro Rolando ORCID; Elezgarai Gabantxo, Izaskun ORCID (Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2018)
      Endokannabinoide-sistema (EKS) zelulen arteko komunikazio-sistema fisiologiko neuromodulatzaile garrantzitsuenetako bat da, eta helduaroan beraren funtzio ezagunena neurotransmisoreen doikuntza da. Azken urteotako ikerketek, ...
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      Environmental Enrichment Rescues Endocannabinoid-Dependent Synaptic Plasticity Lost in Young Adult Male Mice after Ethanol Exposure during Adolescence 

      Rico Barrio, Irantzu; Peñasco Iglesias, Sara; Lecumberri Odriozola, Leire; Serrano Murgia, Maitane ORCID; Egaña Huguet, Jon; Mimenza Saiz, Amaia; Soria Gómez, Edgar ORCID; Ramos Uriarte, Almudena ORCID; Buceta Salazar, Ianire ORCID; Gerrikagoitia Marina, Inmaculada ORCID; Mendizabal Zubiaga, Juan Luis ORCID; Elezgarai Gabantxo, Izaskun ORCID; Puente Bustinza, Nagore ORCID; Grandes Moreno, Pedro Rolando ORCID (MDPI, 2021-07-16)
      Binge drinking (BD) is a serious health concern in adolescents as high ethanol (EtOH) consumption can have cognitive sequelae later in life. Remarkably, an enriched environment (EE) in adulthood significantly recovers ...
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      Impact of the transient receptor potential vanilloid 1 deletion on the endocannabinoid system in the mouse dentate gyrus 

      Egaña Huguet, Jon (2020-06-19)
      En este trabajo de tesis doctoral se ha analizado como la delección genética de un receptor afecta al resto del sistema con el que interactúa. Más concretamente, se ha establecido cuáles han sido los cambios en el sistema ...
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      Lack of the transient receptor potential vanilloid 1 shifts cannabinoid-dependent excitatory synaptic plasticity in the dentate gyrus of the mouse brain hippocampus 

      Egaña Huguet, Jon; Saumell Esnaola, Miquel; Achicallende Urcaregui, Svein ORCID; Soria Gómez, Edgar ORCID; Bonilla del Río, Itziar; García del Caño, Gontzal; Barrondo Lacarra, Sergio ORCID; Sallés Alvira, Joan; Gerrikagoitia Marina, Inmaculada ORCID; Puente Bustinza, Nagore ORCID; Elezgarai Gabantxo, Izaskun ORCID; Grandes Moreno, Pedro Rolando ORCID (Frontiers Media, 2021-07-07)
      [EN] The transient receptor potential vanilloid 1 (TRPV1) participates in synaptic functions in the brain. In the dentate gyrus, post-synaptic TRPV1 in the granule cell (GC) dendritic spines mediates a type of long-term ...
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      The Absence of the Transient Receptor Potential Vanilloid 1 Directly Impacts on the Expression and Localization of the Endocannabinoid System in the Mouse Hippocampus 

      Egaña Huguet, Jon; Bonilla del Río, Itziar; Gómez Urquijo, Sonia María ORCID; Mimenza Saiz, Amaia; Saumell Esnaola, Miquel; Borrega Román, Leire; García del Caño, Gontzal; Sallés Alvira, Joan; Puente Bustinza, Nagore ORCID; Gerrikagoitia Marina, Inmaculada ORCID; Elezgarai Gabantxo, Izaskun ORCID; Grandes Moreno, Pedro Rolando ORCID (Frontiers Media, 2021-02-22)
      The transient receptor potential vanilloid 1 (TRPV1) is a non-selective ligand-gated cation channel involved in synaptic transmission, plasticity, and brain pathology. In the hippocampal dentate gyrus, TRPV1 localizes to ...
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      The Endocannabinoid System in Glial Cells and Their Profitable Interactions to Treat Epilepsy: Evidence from Animal Models 

      Egaña Huguet, Jon; Soria Gómez, Edgar ORCID; Grandes Moreno, Pedro Rolando ORCID (MDPI, 2021-12-08)
      Epilepsy is one of the most common neurological conditions. Yearly, five million people are diagnosed with epileptic-related disorders. The neuroprotective and therapeutic effect of (endo)cannabinoid compounds has been ...
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      Up-regulation of CB1 Cannabinoid Receptors Located at Glutamatergic Terminals in the Medial Prefrontal Cortex of the Obese Zucker Rat. 

      Echeazarra, Leyre; Barrondo Lacarra, Sergio ORCID; García del Caño, Gontzal; Bonilla del Río, Itziar; Egaña Huguet, Jon; Puente Bustinza, Nagore ORCID; Aretxabala Rodríguez, Xabier; Montaña, Mario; López de Jesús, Maider ORCID; González Burguera, Imanol; Saumell Esnaola, Miquel; Goicolea Altuna, María Aranzazu ORCID; Grandes Moreno, Pedro Rolando ORCID; Sallés Alvira, Joan (Frontiers Media, 2022-10-18)
      The present study describes a detailed neuroanatomical distribution map of the cannabinoid type 1 (CB1) receptor, along with the biochemical characterization of the expression and functional coupling to their cognate G i/o ...