Browsing by Author "Barreda Gómez, Gabriel"
Now showing items 21-28 of 28
-
Neuroanatomical characterization of the G protein-coupled receptor activity evoked by galanin-related ligands
Galanin neuropeptide is distributed throughout the mammalian nervous system modulating a plethora of diverse physiological functions, including nociception, cognition and neuroendocrine regulation. The regulation of the ... -
Neuroinflammation in the Evolution of Motor Function in Stroke and Trauma Patients: Treatment and Potential Biomarkers
Larrea, Ane; Elexpe, Ane; Díez-Martín, Eguzkiñe; Torrecilla Sesma, María; Astigarraga Arribas, Egoitz; Barreda Gómez, Gabriel (MDPI, 2023-10-25)
Neuroinflammation has a significant impact on different pathologies, such as stroke or spinal cord injury, intervening in their pathophysiology: expansion, progression, and resolution. Neuroinflammation involves oxidative ... -
Novel proteomic and lipidomic biomarkers for limbal epithelial stem cell identification and corneal transplant monitoring
Rodríguez Astigarraga, Maddalen (2022-07-28)El objeto de esta tesis doctoral ha sido la caracterización proteómica y lipidómica de cinco poblaciones celulares de la córnea humana para la identificación de nuevos biomarcadores de cada tipo celular. Además, se han ... -
Review of Technological Challenges in Personalised Medicine and Early Diagnosis of Neurodegenerative Disorders
Domínguez Fernández, Celtia; Egiguren Ortiz, June; Razquin Lizarraga, Jone; Gómez Galán, Margarita; De las Heras García, Laura; Paredes Rodriguez, Elena; Astigarraga Arribas, Egoitz; Miguelez Palomo, Cristina; Barreda Gómez, Gabriel (MDPI, 2023-02-07)Neurodegenerative disorders are characterised by progressive neuron loss in specific brain areas. The most common are Alzheimer’s disease and Parkinson’s disease; in both cases, diagnosis is based on clinical tests with ... -
Serological Antibodies against Kidney, Liver, and Spleen Membrane Antigens as Potential Biomarkers in Patients with Immune Disorders
Hernández Suárez, Leidi; Díez Martín, Eguzkiñe; Egiguren Ortiz, June; Fernández, Roberto; Etxebarria Gallego, Aitor; Astigarraga Arribas, Egoitz; Miguélez Palomo, Cristina; Ramírez Garcia, Andoni; Barreda Gómez, Gabriel (MDPI, 2024-02-07)Immune disorders arise from complex genetic and environmental factors, which lead to dysregulation at the cellular and inflammatory levels and cause tissue damage. Recent research highlights the crucial role of reactive ... -
Spinal Inhibition of GABAB Receptors by the Extracellular Matrix Protein Fibulin-2 in Neuropathic Rats
Papon, Marie Amélie; Le Feuvre, Yves; Barreda Gómez, Gabriel; Favereaux, Alexandre; Farrugia, Fanny; Bouali Benazzouz, Rabia; Nagy, Frédéric; Rodríguez Puertas, Rafael; Landry, Marc (Frontiers Media, 2020-07-15)
In the central nervous system, the inhibitory GABAB receptor is the archetype of heterodimeric G protein-coupled receptors (GPCRs). Receptor interaction with partner proteins has emerged as a novel mechanism to alter GPCR ... -
Study of Tissue-Specific Reactive Oxygen Species Formation by Cell Membrane Microarrays for the Characterization of Bioactive Compounds
Elexpe, Ane; Nieto, Nerea; Fernández Cuétara, Claudia; Domínguez Fernández, Celtia; Morera Herreras, Teresa; Torrecilla Sesma, María; Miguélez Palomo, Cristina; Laso, Antonio; Ochoa, Eneko; Bailen, María; González Coloma, Azucena; Angulo Barturen, Iñigo; Astigarraga, Egoitz; Barreda Gómez, Gabriel (MDPI, 2021-11-29)
The production of reactive oxygen species (ROS) increases considerably in situations of cellular stress, inducing lipid peroxidation and multiple alterations in proteins and nucleic acids. However, sensitivity to oxidative ... -
Upregulated phospholipase D2 expression and activity is related to the metastatic properties of melanoma
Pérez Valle, Arantza; Ochoa Olascoaga, Begoña; Shah, Krushangi N.; Barreda Gómez, Gabriel; Astigarraga Arribas, Egoitz; Boyano López, María Dolores; Asumendi Mallea, Aintzane
(Spandidos, 2022-05)
[EN] The incidence rates of melanoma have increased steadily in recent decades and nearly 25% of the patients diagnosed with early-stage melanoma will eventually develop metastasis, for which there is currently no fully ...