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      A Morphological Method for Ammonia Detection in Liver 

      Gutiérrez de Juan, Virginia; López de Davalillo, Sergio; Fernández Ramos, David; Barbier Torres, Lucía; Zubiete Franco, Imanol; Fernández Tussy, Pablo; Simón Espinosa, Jorge; Lopitz Otsoa, Fernando; De las Heras Montero, Javier Adolfo; Iruzubieta, Paula; Arias Loste, María Teresa; Villa, Erica; Crespo, Javier; Andrade, Raúl; Lucena, M. Isabel; Varela Rey, Marta; Lu, Shelly C.; Mato, José M.; Cardoso Delgado, Teresa de Jesús; Martínez Chantar, María Luz ORCID (Public Library Science, 2017-03-20)
      Hyperammonemia is a metabolic condition characterized by elevated levels of ammonia and a common event in acute liver injury/ failure and chronic liver disease. Even though hepatic ammonia levels are potential predictive ...
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      Beneficial effect of ursodeoxycholic acid in patients with acyl-CoA oxidase 2 (ACOX2) deficiency-associated hypertransaminasemia 

      Alonso Peña, Marta; Espinosa Escudero, Ricardo; Herráez Aguilar, Elisa; Briz Sánchez, Oscar; Cagigal, María Luisa; González Santiago, Jesús M.; Ortega Alonso, Aida; Fernández Rodríguez, Conrado; Bujanda Fernández de Pierola, Luis ORCID; Calvo Sánchez, Marta; D'Avola, Delia; Londono, Maria Carlota; Diago, Moisés; Fernández Checa, José Carlos; García Ruiz, Carmen; Andrade, Raúl; Lammert, Frank; Prieto, Jesús; Crespo, Javier; Juanpérez, Javier; Díaz González, Álvaro; Monte, María J.; García Marín, Jose Juan (Wiley, 2022-11)
      Background and Aims: A variant (p.Arg225Trp) of peroxisomal acyl-CoA oxidase 2 (ACOX2), involved in bile acid (BA) side-chain shortening, has been associated with unexplained persistent hypertransaminasemia and ...
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      Restoring cellular magnesium balance through Cyclin M4 protects against acetaminophen-induced liver damage 

      González Recio, Irene; Simón Espinosa, Jorge; Goikoetxea Usandizaga, Naroa; Serrano Maciá, Marina; Mercado Gómez, María; Rodríguez Agudo, Rubén; Lachiondo Ortega, Sofía; Gil Pitarch, Clàudia; Fernández Rodríguez, Carmen; Castellana, Donatello; Latasa, María Ujué; Abecia Aliende, Leticia ORCID; Anguita Castillo, Juan de Dios; Delgado, Teresa C.; Iruzubieta, Paula; Crespo, Javier; Hardy, Serge; Petrov, Petar D.; Jover, Ramiro; Ávila, Matías A. ORCID; Martín Plágaro, César Augusto; Schaeper, Ute; Tremblay, Michel L.; Dear, James W.; Masson, Steven; McCain, Misti Vanette; Reeves, Helen L.; Andrade, Raúl; Lucena, M. Isabel; Buccella, Daniela; Martínez de la Cruz, Alfonso; Martínez Chantar, María Luz ORCID (Nature, 2022-11)
      Drug induced liver injury (DILI) is an important cause acute liver failure. Here the authors report that serum Mg2+ serum levels decrease in patients with DILI as well as in preclinical animal models treated with acetaminophen ...