Browsing by Author "Artusa, Valentina"

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      New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants 

      Romerio, Alessio; Gotri, Nicole; Franco, Ana Rita; Artusa, Valentina; Shaik, Mohammed Monsoor; Pasco, Samuel T.; Atxabal Arrasate, Unai; Matamoros Recio, Alejandra; Mínguez Toral, Marina; Zalamea, Juan Diego; Franconetti García, Antonio; Abrescia, Nicola G. A.; Jiménez Barbero, Jesús ORCID; Anguita Castillo, Juan de Dios; Martín Santamaría, Sonsoles; Peri, Francesco (American Chemical Society, 2023-02)
      We disclose here a panel of small-molecule TLR4 agonists (the FP20 series) whose structure is derived from previously developed TLR4 ligands (FP18 series). The new molecules have increased chemical stability and a shorter, ...