Browsing by Author "Ashrafizadeh, Milad"
Now showing items 1-4 of 4
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Advances in understanding the role of P-gp in doxorubicin resistance: Molecular pathways, therapeutic strategies, and prospects
Mirzaei, Sepideh; Gholami, Mohammad Hossein; Hashemi, Farid; Zabolian, Amirhossein; Vasheghani Farahani, Mahdi; Hushmandi, Kiavash; Zarrabi, Ali; Goldman, Aaron; Ashrafizadeh, Milad; Orive Arroyo, Gorka (Elsevier, 2022-02)P-glycoprotein (P-gp) is a drug efflux transporter that triggers doxorubicin (DOX) resistance. In this review, we highlight the molecular avenues regulating P-gp, such as Nrf2, HIF-1alpha, miRNAs, and long noncoding ... -
AIE-featured tetraphenylethylene nanoarchitectures in biomedical application: Bioimaging, drug delivery and disease treatment
Sarathkumar, Kothanahally S.; Girish, Yarabahally R.; Ashrafizadeh, Milad; Mirzaei, Sepideh; Rakesh, Kadalipura P.; Gholami, Mohammad Hossein; Zabolian, Amirhossein; Hushmandi, Kiavash; Orive Arroyo, Gorka; Kadumudi, Firoz Babu; Dolatshahi-Pirouz, Alireza ; Thakur, Vijay Kumar; Zarrabi, Ali; Makvandi, Pooyan; Rangappa, Kanchugarakoppal S. (Elsevier, 2021-11-15)[EN]The development of aggregation-induced emission (AIE) has received extreme considerations from basic and clinical researches. To date, various luminogens with AIE property (AIEgens) have been broadly utilized in ... -
Chitosan-based nanoscale systems for doxorubicin delivery: Exploring biomedical application in cancer therapy
Ashrafizadeh, Milad; Hushmandi, Kiavash; Mirzaei, Sepideh; Bokaie, Saied; Bigham, Ashkan; Makvandi, Pooyan; Rabiee, Navid; Thakur, Vijay Kumar; Kumar, Alan Prem; Sahrifi, Esmaeel; Varma, Rajender S.; Aref, Amir Reza; Wojnilowicz, Marcin; Zarrabi, Ali; Karimi-Maleh, Hassan; Voelcker, Nicolas H.; Mostafavi, Ebrahim; Orive Arroyo, Gorka (Wiley, 2023-01)Green chemistry has been a growing multidisciplinary field in recent years showing great promise in biomedical applications, especially for cancer therapy. Chitosan (CS) is an abundant biopolymer derived from chitin and ... -
Hyaluronic acid-based nanoplatforms for Doxorubicin: A review of stimuli-responsive carriers, co-delivery and resistance suppression
Ashrafizadeh, Milad; Mirzaei, Sepideh; Gholami, Mohammad Hossein; Hashemi, Farid; Zabolian, Amirhossein; Raei, Mehdi; Hushmandi, Kiavash; Zarrabi, Ali; Voelcker, Nicolas H.; Aref, Amir Reza; Hamblin, Michael R.; Varma, Rajender S.; Samarghandian, Saeed; Arostegi, I. J.; Alzola, M.; Kumar, Alan Prem; Thakur, Vijay Kumar; Nabavi, Noushin; Makvandi, Pooyan; Tay, Franklin R.; Orive Arroyo, Gorka (Elsevier, 2021-11-15)[EN]An important motivation for the use of nanomaterials and nanoarchitectures in cancer therapy emanates from the widespread emergence of drug resistance. Although doxorubicin (DOX) induces cell cycle arrest and DNA damage ...