Browsing by Author "Astigarraga, Egoitz"
Now showing items 1-3 of 3
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Enzyme Therapy: Current Challenges and Future Perspectives
De la Fuente López, Miguel; Lombardero, Laura; Gómez-González, Alfonso; Solari, Cristina; Angulo Barturen, Iñigo; Acera Osa, Arantxa; Vecino Cordero, Elena ; Astigarraga, Egoitz; Barreda Gómez, Gabriel (MDPI, 2021-08-25)In recent years, enzymes have risen as promising therapeutic tools for different pathologies, from metabolic deficiencies, such as fibrosis conditions, ocular pathologies or joint problems, to cancer or cardiovascular ... -
Lipid fingerprint-based histology accurately classifies nevus, primary melanoma, and metastatic melanoma samples
Huergo Baños, Cristina; Velasco, Verónica; Garate Yeregui, Jone; Fernández Regueira, Roberto Antonio ; Martín Allende, Javier; Zabalza Estévez, Ignacio; Artola Igarza, Juan Luis; Martí Laborda, Rosa María; Asumendi Mallea, Aintzane ; Astigarraga, Egoitz; Barreda Gómez, Gabriel; Fresnedo Aranguren, María Olatz; Ochoa Olascoaga, Begoña; Boyano López, María Dolores ; Fernández González, José Andrés (Wiley, 2024-02)Probably, the most important factor for the survival of a melanoma patient is early detection and precise diagnosis. Although in most cases these tasks are readily carried out by pathologists and dermatologists, there are ... -
Study of Tissue-Specific Reactive Oxygen Species Formation by Cell Membrane Microarrays for the Characterization of Bioactive Compounds
Elexpe, Ane; Nieto, Nerea; Fernández Cuétara, Claudia; Domínguez Fernández, Celtia; Morera Herreras, Teresa; Torrecilla Sesma, María ; Miguélez Palomo, Cristina; Laso, Antonio; Ochoa, Eneko; Bailen, María; González Coloma, Azucena; Angulo Barturen, Iñigo; Astigarraga, Egoitz; Barreda Gómez, Gabriel (MDPI, 2021-11-29)The production of reactive oxygen species (ROS) increases considerably in situations of cellular stress, inducing lipid peroxidation and multiple alterations in proteins and nucleic acids. However, sensitivity to oxidative ...