Browsing by Author "Barrenechea, Maitane"
Now showing items 1-5 of 5
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Association of retinal neurodegeneration with the progression of cognitive decline in Parkinson’s disease
Murueta-Goyena Larrañaga, Ane; Romero Bascones, David; Teijeira Portas, Sara; Aritz Urcola, Javier; Ruiz Martínez, Javier; Del Pino Sáez, Rocío; Acera Gil, María Ángeles; Petzold, Axel; Wagner, Siegfried Karl; Keane, Pearse Andrew; Ayala Fernández, Unai; Barrenechea, Maitane; Tijero Merino, Beatriz; Gómez Esteban, Juan Carlos; Gabilondo Cuellar, Iñigo (Nature, 2024-01)Retinal thickness may serve as a biomarker in Parkinson’s disease (PD). In this prospective longitudinal study, we aimed to determine if PD patients present accelerated thinning rate in the parafoveal ganglion cell-inner ... -
Foveal Pit Morphology Characterization: A Quantitative Analysis of the Key Methodological Steps
Romero-Bascones, David; Barrenechea, Maitane; Murueta-Goyena Larrañaga, Ane; Galdós Iztueta, Marta; Gómez Esteban, Juan Carlos; Gabilondo Cuellar, Iñigo; Ayala, Unai (MDPI, 2021-06-01)Disentangling the cellular anatomy that gives rise to human visual perception is one of the main challenges of ophthalmology. Of particular interest is the foveal pit, a concave depression located at the center of the ... -
Foveal remodeling of retinal microvasculature in Parkinson’s disease
Murueta-Goyena Larrañaga, Ane; Barrenechea, Maitane; Erramuzpe Aliaga, Asier; Teijeira Portas, Sara; Pengo, Marta; Ayala Fernández, Unai; Romero Bascones, David; Acera, Marian; Del Pino Sáez, Rocío; Gómez Esteban, Juan Carlos; Gabilondo Cuellar, Iñigo (Frontiers Media, 2021-07-12)[EN] Background: Retinal microvascular alterations have been previously described in Parkinson’s disease (PD) patients using optical coherence tomography angiography (OCT-A). However, an extensive description of retinal ... -
Retinal Thickness Predicts the Risk of Cognitive Decline in Parkinson Disease
Murueta-Goyena Larrañaga, Ane; Del Pino Sáez, Rocío; Galdós Iztueta, Marta; Arana Larrea, Begoña; Acera, Marian; Carmona Abellán, Mar; Fernández Valle, Tamara; Tijero Merino, Beatriz; Lucas Jiménez, Olaia; Ojeda, Natalia; Ibarretxe Bilbao, Naroa; Peña, Javier; Cortés, Jesús M.; Ayala Fernández, Unai; Barrenechea, Maitane; Gómez Esteban, Juan Carlos; Gabilondo Cuellar, Iñigo (Wiley, 2021-01)Objective This study was undertaken to analyze longitudinal changes of retinal thickness and their predictive value as biomarkers of disease progression in idiopathic Parkinson's disease (iPD). Methods Patients with ... -
Spatial characterization of the effect of age and sex on macular layer thicknesses and foveal pit morphology
Romero Bascones, David; Ayala Fernández, Unai; Alberdi Aramendi, Ane; Erramuzpe Aliaga, Asier; Galdós Iztueta, Marta; Gómez Esteban, Juan Carlos; Murueta-Goyena Larrañaga, Ane; Teijeira Portas, Sara; Gabilondo Cuellar, Iñigo; Barrenechea, Maitane (Public Library Science, 2022-12)Characterizing the effect of age and sex on macular retinal layer thicknesses and foveal pit morphology is crucial to differentiating between natural and disease-related changes. We applied advanced image analysis techniques ...