Browsing by Author "Barroso Gomila, Orhi"

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      Development of biotin-based strategies to dissect the ubiquitin code. 

      Barroso Gomila, Orhi (2022-12-15)
      La naturaleza dinámica y reversible de las modificaciones post-traduccionales por parte de los miembros de la familia de la ubiquitina plantea importantes desafíos durante su investigación. En esta Tesis presentamos dos ...
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      Identification of proximal SUMO-dependent interactors using SUMO-ID 

      Barroso Gomila, Orhi; Trulsson, Erik; Muratore, Verónica; Canosa, Iñigo; Merino Cacho, Laura; Cortázar, Ana Rosa; Pérez Fernández, Coralia; Azkargorta, Mikel; Iloro, Ibon; Carracedo Pérez, Arkaitz ORCID; Aransay Bañares, Ana María; Elortza, Felix; Mayor Martínez, Ugo ORCID; Verteegal, Alfred C.O.; Barrio Olano, María Rosa; Sutherland, James D. (Nature Research, 2021-11-18)
      [EN]The fast dynamics and reversibility of posttranslational modifications by the ubiquitin family pose significant challenges for research. Here we present SUMO-ID, a technology that merges proximity biotinylation by ...
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      SALL1 Modulates CBX4 Stability, Nuclear Bodies, and Regulation of Target Genes 

      Giordano, Immacolata; Pirone, Lucia; Muratore, Veronica; Landaluze, Eukene; Pérez, Coralia; Lang, Valerie; Garde-Lapido, Elisa; González López, Monika; Barroso Gomila, Orhi; Vertegaal, Alfred C. O.; Aransay Bañares, Ana María; Rodríguez Pérez, José Antonio ORCID; Rodriguez, Manuel S.; Sutherland, James D; Barrio Olano, María Rosa (Frontiers Media, 2021-09-21)
      Development is orchestrated through a complex interplay of multiple transcription factors. The comprehension of this interplay will help us to understand developmental processes. Here we analyze the relationship between ...
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      SUMOylation in the control of cholesterol homeostasis 

      Talamillo, Ana; Ajuria, Leiore; Grillo, Marco; Barroso Gomila, Orhi; Mayor Martínez, Ugo ORCID; Barrio Olano, María Rosa (The Royal Society, 2020-05)
      SUMOylation-protein modification by the small ubiquitin-related modifier (SUMO)-affects several cellular processes by modulating the activity, stability, interactions or subcellular localization of a variety of substrates. ...
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      The role of SUMOylation during development 

      Talamillo, Ana; Barroso Gomila, Orhi; Giordano, Immacolata; Ajuria, Leiore; Grillo, Marco; Mayor Martínez, Ugo ORCID; Barrio Olano, María Rosa (Portland Press, 2020-04)
      During the development of multicellular organisms, transcriptional regulation plays an important role in the control of cell growth, differentiation and morphogenesis. SUMOylation is a reversible post-translational process ...