Browsing by Author "Bayón Cordero, Laura"
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Application of Solid Lipid Nanoparticles to Improve the Efficiency of Anticancer Drugs
Bayón Cordero, Laura; Alcorta Calvo, Miren Itziar; Arana Urbieta, Lide (MDPI, 2019-03-22)Drug delivery systems have opened new avenues to improve the therapeutic effects of already-efficient molecules. Particularly, Solid Lipid Nanoparticles (SLNs) have emerged as promising nanocarriers in cancer therapy. SLNs ... -
Expression and Function of GABA Receptors in Myelinating Cells
Serrano Regal, María Paz; Bayón Cordero, Laura; Ordaz, Rainald Pablo; Garay, Edith; Limon, Agenor; Arellano, Rogelio O.; Matute Almau, Carlos José; Sánchez Gómez, María Victoria (Frontiers Media, 2020-08-21)Myelin facilitates the fast transmission of nerve impulses and provides metabolic support to axons. Differentiation of oligodendrocyte progenitor cells (OPCs) and Schwann cell (SC) precursors is critical for myelination ... -
GABAB receptor in oligodendrocytes and its therapeutic potential against demyelinating diseases
Bayón Cordero, Laura (2024-05-31)In this doctoral thesis, we have identified the differentiation mechanisms influenced by GABAB receptor (GABABR) in oligodendrocytes and we have examined its potential for (re)myelination. First, we evaluated the consequences ... -
Genetically modified macrophages accelerate myelin repair
Aigrot, Marie Stephane; Barthelemy, Clara; Moyon, Sarah; Dufayet-Chaffaud, Gaelle; Izagirre Urizar, Leire; Gillet-Legrand, Beatrix; Tada, Satoru; Bayón Cordero, Laura; Chara Ventura, Juan Carlos; Matute Almau, Carlos José; Cartier, Nathalie; Lubetzki, Catherine; Tepavcevic, Vanja (Wiley, 2022-08-08)[EN] Preventing neurodegeneration-associated disability progression in patients with multiple sclerosis (MS) remains an unmet therapeutic need. As remyelination prevents axonal degeneration, promoting this process in ... -
Relevancia del receptor GABAB en el proceso de mielinización durante el desarrollo en rata
Luengas Escuza, Irene (2020-12-15)[ES] En enfermedades desmielinizantes como la esclerosis múltiple los oligodendrocitos, responsables de la mielinización en el sistema nervioso central, y las vainas de mielina que rodean los axones resultan dañados, ... -
Solid Lipid Nanoparticles Surface Modification Modulates Cell Internalization and Improves Chemotoxic Treatment in an Oral Carcinoma Cell Line
Arana Urbieta, Lide; Bayón Cordero, Laura; Sarasola Telleria, Laura Isabel; Berasategi, Miren; Ruiz, Sandra; Alcorta Calvo, Miren Itziar (MDPI, 2019-03-20)Solid lipid nanoparticles (SLN) present low toxicity, versatility to incorporate both lipophilic and hydrophilic drugs, controlled drug release and they are easy to scale-up. It is well known that the endocytosis pathway ...