ItzuliZerendatu honen arabera: egilea"Beloqui Elizazu, Ana"
13-tik 1-13 emaitza erakusten
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A Versatile Chemoenzymatic Nanoreactor that Mimics NAD(P)H Oxidase for the In Situ Regeneration of Cofactors
(Wiley, 2022-09)Herein, we report a multifunctional chemoenzymatic nanoreactor (NanoNOx) for the glucose-controlled regeneration of natural and artificial nicotinamide cofactors. NanoNOx are built of glucose oxidase-polymer hybrids that ... -
An Emerging Nanozyme Class for à la carte Enzymatic-Like Activities based on Protein-Metal Nanocluster Hybrids
; ; ; ; López Cortajarena, Aitziber
(Wiley, 2023-09)
In this study, the goal is to fabricate robust and highly efficient peroxidase-like nanozymes that can ultimately be assembled into films for their easy reuse in catalytic cycles. Nanozymes are designed by mimicking the ... -
Dressing enzymes with tailored nanogels as a versatile approach for the development of heterogeneous biocatalysts.
(2022-12-16)El número de aproximaciones para la inmovilización de enzimas está creciendo rápidamente debido a los avances en el campo de la biotecnología, la química de polímeros y la nanotecnología. Las enzimas son excelentes ... -
Elastomeric protein bioactive eutectogels for topical drug delivery
; ; ; ; ; ; ; Larrañaga Espartero, Aitor; ; ; (Wiley, 2024-05)
Therapeutic deep eutectic solvents (THEDES) are an emerging family of eutectic mixtures gaining increasing interest in the biomedical space. The immobilization of THEDES into polymer networks allows bioactive eutectogels ... -
Engineered metal-loaded biohybrids to promote the attachment and electron-shuttling between enzymes and carbon electrodes
(Wiley, 2024-05)The inorganic content and the catalytic performance pose metal-loaded enzyme nanoflowers as promising candidates for developing bioelectrodes capable of functioning without the external addition of a redox mediator. However, ... -
Hetero-Diels-Alder Cycloaddition with RAFT Polymers as Bioconjugation Platform
(Wiley, 2020-11-02)We introduce the bioconjugation of polymers synthesized by RAFT polymerization, bearing no specific functional end group, by means of hetero-Diels-Alder cycloaddition through their inherent terminal thiocarbonylthio moiety ... -
In vitro Production of Hemin-Based Artificial Metalloenzymes
; ; ; ; López Cortajarena, Aitziber (Wiley, 2024-02)
Developing enzyme alternatives is pivotal to improving and enabling new processes in biotechnology and industry. Artificial metalloenzymes (ArMs) are combinations of protein scaffolds with metal elements, such as metal ... -
Inmovilización de biocatalizadores en reactores estructurados para la eliminación de fenoles y tintes en aguas
(2022-10-18)En el presente trabajo se ha llevado a cabo la síntesis y caracterización de un soporte mesoporoso de sílica, para la inmovilización de biocatalizadores en reactores estructurados. La gran área superficial de este soporte, ... -
Metal-Organic Enzyme Nanogels as Nanointegrated Self-Reporting Chemobiosensors
(American Chemical Society, 2022)[EN] A fluorometric glucose biosensor based on fine-tuned chemoenzymatic nanohybrids is herein proposed. The successful integration of an engineered glucose oxidase enzyme and an optically responsive polymeric nanogel in ... -
Nanozymes with versatile redox capabilities inspired in metalloenzymes
; ; ; ; ; López Cortajarena, Aitziber (RSC, 2023)
Metalloenzymes represent exemplary systems in which an organic scaffold combines with a functional inorganic entity, resulting in excellent redox catalysts. Inspired by these natural hybrid biomolecules, biomolecular ... -
Recent advances and future perspectives on porous materials for biomedical applications
; Sanz Iturralde, Oihane; ; ; (Future Medicine Ltd, 2022-01-13)
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Tunable Polymeric Scaffolds for Enzyme Immobilization
(Frontiers Media, 2020-07-30)The number of methodologies for the immobilization of enzymes using polymeric supports is continuously growing due to the developments in the fields of biotechnology, polymer chemistry, and nanotechnology in the last years. ... -
Unveiling the Potential of Surface Polymerized Drug Nanocrystals in Targeted Delivery
(ACS, 2024-09)Nanocrystals (NCs) have entirely changed the panorama of hydrophobic drug delivery, showing improved biopharmaceutical performance through multiple administration routes. NCs are potential highly loaded nanovectors due to ...