Browsing by Author "Bruinsma, Wytse"
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Inhibition of Polo-like kinase 1 during the DNA damage response is mediated through loss of Aurora A recruitment by Bora
Bruinsma, Wytse; Aprelia, Melinda; García Santisteban, Iraia ; Kool, Jeroen; Xu, Yan Juan; Medema, René H. (Nature Publishing Group, 202016-10-)When cells in G2 phase are challenged with DNA damage, several key mitotic regulators such as Cdk1/Cyclin B, Aurora A and Plk1 are inhibited to prevent entry into mitosis. Here we have studied how inhibition of Plk1 is ...