• Thumbnail

      Association of Notch-1, osteopontin and stem-like cells in ENU-glioma malignant process 

      Bulnes Sesma, Susana; Bermúdez, Garazi; Lafuente Sánchez, José Vicente ORCID (Impact Journals LLC, 2018-07-31)
      Notch-1 and osteopontin (OPN) mediate angiogenesis and glioma stem-like cell (GSLC) maintenance. However, the relationship between these molecules and GSLCs during the development of glioma is unknown. We investigate the ...
    • Thumbnail

      Differential Exposure to N-Ethyl N-Nitrosourea During Pregnancy is Relevant to the Induction of Glioma and PNSTs in the Brain 

      Bulnes Sesma, Susana; Murueta-Goyena Larrañaga, Ane; Lafuente Sánchez, José Vicente ORCID (Elsevier, 2021-05-26)
      Exposure to N-nitroso compounds (NOCs) during pregnancy has been associated with an increase in brain tumors in the progeny. This study investigated the brain tumorigenic effect of N-ethyl N-nitrosourea (ENU) after ...
    • Thumbnail

      Distribution of stem cells inside induced gliomas by ethyl-nitrosurea 

      García Blanco, Alvaro (2014-12-19)
      Los gliomas son tumores del sistema nervioso central de carácter difuso y con una alta vascularización. Las células que guían el crecimiento y expansión tumoral son las células madre tumorales que hay en el interior ...
    • Thumbnail

      Gliometako zelula nestina-positiboen banaketa 

      Iriondo Juaristi, Ane ORCID; Bulnes Sesma, Susana; García Blanco, A.; Bengoetxea, H.; Lafuente Sánchez, José Vicente ORCID (Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitatearen Argitalpen Zerbitzua, 2014)
      Zelula ama tumoralak (ZAT), ze lula amen ezaugarriak dituzten eta tumore bat birsortzeko gaitasuna duten tumore-ze1ulak dira. Bai anima1ietan eta bai gizakietan ere , multzoka agertzen dira eremu peribaskularrean, askotan ...
    • Thumbnail

      Murine femur micro-computed tomography and biomechanical datasets for an ovariectomy-induced osteoporosis model 

      Stephens, Maialen; López Linares, Karen; Aldazabal Rego, Javier; Macías García, Iratxe; Ortuzar Markes, Naiara; Bengoetxea Odriozola, Harkaitz; Bulnes Sesma, Susana; Alcorta Sevillano, Natividad; Infante, Arantza; Lafuente Sánchez, José Vicente ORCID; Rodríguez, Clara I. (Nature Research, 2021-09-15)
      The development of new effective and safer therapies for osteoporosis, in addition to improved diagnostic and prevention strategies, represents a serious need in the scientific community. Micro-CT image-based analyses in ...