Browsing by Author "Canbay, Ali"

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      A Review of the Epidemiology, Pathophysiology, and Efficacy of Anti-diabetic Drugs Used in the Treatment of Nonalcoholic Fatty Liver Disease 

      Manka, Paul P.; Kaya, Eda; Canbay, Ali; Syn, Wing-Kin (Springer, 2021-08-19)
      In recent years, epidemiological studies have consistently demonstrated that the coexistence of nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) is strongly associated with increased mortality ...
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      Anti-TNFα treatment in Crohn’s disease: Impact on hepatic steatosis, gut-derived hormones and metabolic status 

      Manka, Paul; Sydor, Svenja; Wase, Nishikant; Best, Jan; Brandenburg, Malte; Hellbeck, Annika; Schänzer, Julia; Vilchez-Vargas, Ramiro; Link, Alexander; Figge, Anja; Jähnert, Andreas; Von Arnim, Ulrike; Coombes, Jason D.; Cubero, Francisco-Javier; Kahraman, Alisan; Kim, Moon-Sung; Kälsch, Julia; Kinner, Sonja; Faber, Klaas-Nico; Moshage, Han; Gerken, Guido; Syn, Wing-Kin; Friedman, Scott L.; Canbay, Ali; Bechmann, Lars P. (Wiley, 2021-11)
      Background and Aims An association between Crohn's disease (CD) and hepatic steatosis has been reported. However, the underlying mechanisms of steatosis progression in CD are not clear. Among the most effective CD treatments ...
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      Hepatokines and adipokines in NASH-related hepatocellular carcinoma 

      Kucukoglu, Ozlem; Sowa, Jan Peter; Mazzolini, Guillermo; Syn, Wing-Kin; Canbay, Ali (Elsevier, 2020-11-05)
      Summary The incidence of hepatocellular carcinoma (HCC) is increasing in industrialised societies; this is likely secondary to the increasing burden of non-alcoholic fatty liver disease (NAFLD), its progressive form ...
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      rs641738C>T nearMBOAT7is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis 

      Teo, Kevin; Abeysekera, Kushala W.M.; Adams, Leon; Aigner, Elmar; Anstee, Quentin M.; Bañales Asurmendi, Jesús María ORCID; Banerjee, Rajarshi; Basu, Priyadarshi; Berg, Thomas; Bhatnagar, Pallav; Buch, Stephan; Canbay, Ali; Caprio, Sonia; Chatterjee, Ankita; Chen, Yii-Der Ida; Chowdhury, Abhijit; Daly, Ann K.; Datz, Christian; De Gracia Hahn, Dana; DiStefano, Johanna K.; Dong, Jiawen; Duret, Amedine; EU-PNAFLD Investigators; Emdin, Connor; Fairey, Madison; Gerhard, Glenn S.; GOLD Consortium; Guo, Xiuqing; Hampe, Jochen; Hickman, Matthew; Heintz, Lena; Hudert, Christian; Hunter, Harriet; Kelly, Matt; Kozlitina, Julia; Krawczyk, Marcin; Lammert, Frank; Langenberg, Claudia; Lavine, Joel; Li, Lin; Lim, Hong Kai; Loomba, Rohit; Luukkonen, Panu K.; Melton, Phillip E.; Mori, Trevor A.; Palmer, Nicholette D.; Parisinos, Constantinos A.; Pillai, Sreekumar G.; Qayyum, Faiza; Reichert, Matthias C.; Romeo, Stefano; Rotter, Jerome I.; Im, Yu Ri; Santoro, Nicola; Schafmayer, Clemens; Speliotes, Elizabeth K.; Stender, Stefan; Stickel, Felix; Still, Christopher D.; Strnad, Pavel; Taylor, Kent D.; Tybjærg-Hansen, Anne; Umano, Giuseppina Rosaria; Utukuri, Mrudula; Valenti, Luca; Wagenknecht, Lynne E.; Wareham, Nicholas J.; Watanabe, Richard M.; Wattacheril, Julia; Yaghootkar, Hanieh; Yki-Järvinen, Hannele; Young, Kendra A.; Mann, Jake P. (Elsevier, 2021-01)
      Background & Aims: A common genetic variant near MBOAT7 (rs641738C>T) has been previously associated with hepatic fat and advanced histology in NAFLD; however, these findings have not been consistently replicated in the ...
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      Significance of Simple Steatosis: An Update on the Clinical and Molecular Evidence 

      Mazzolini, Guillermo; Sowa, Jan Peter; Atorrasagasti, Catalina; Kucukoglu, Ozlem; Syn, Wing-Kin; Canbay, Ali (MDPI, 2020-11-11)
      Non-alcoholic fatty liver disease (NAFLD) is defined clinicopathologically by the accumulation of lipids in >5% of hepatocytes and the exclusion of secondary causes of fat accumulation. NAFLD encompasses a wide spectrum ...