BackBrowsing by Author "Castelo Careaga, Janire"
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A structurally unique Fusobacterium nucleatum tannase provides detoxicant activity against gallotannins and pathogen resistance
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Abecia Aliende, Leticia
; ; ; ; (Wiley, 2022-02)
Colorectal cancer pathogenesis and progression is associated with the presence of Fusobacterium nucleatum and the reduction of acetylated derivatives of spermidine, as well as dietary components such as tannin-rich foods. ... -
Mitochondrial complex I dysfunction alters the balance of soluble and membrane-bound TNF during chronic experimental colitis.
; ; ; ; ; ; ; ; Fullaondo Elordui-Zapaterieche, Asier; ; ; ; Abecia Aliende, Leticia (Nature, 2022-06)
Inflammatory bowel disease (IBD) is a complex, chronic, relapsing and heterogeneous disease induced by environmental, genomic, microbial and immunological factors. MCJ is a mitochondrial protein that regulates the metabolic ... -
Mitochondrial dysfunction promotes microbial composition that negatively impacts on ulcerative colitis development and progression
; ; ; ; ; ; ; ; ; ; ; Fullaondo Elordui-Zapaterieche, Asier; ; ; ; ; Abecia Aliende, Leticia (Nature, 2023)
Recent evidence demonstrates potential links between mitochondrial dysfunction and inflammatory bowel diseases (IBD). In addition, bidirectional interactions between the intestinal microbiota and host mitochondria may ... -
The commensal bacterium Lactiplantibacillus plantarum imprints innate memory-like responses in mononuclear phagocytes
; Barriales, Diego; Peña Cearra, Ainize; Castelo Careaga, Janire; Palacios, Ainhoa; López, Nerea; Atondo Gondra, Estibaliz; Pascual Itoiz, Miguel Ángel; Martín Ruiz, Itziar; Sampedro, Leticia; González López, Monika; Bárcena, Laura; Martín Mateos, Teresa; Landete, José María; Prados Rosales, Rafael; Plaza Vinuesa, Laura; Muñoz, Rosario; De las Rivas, Blanca; Rodríguez, Juan Miguel; Berra Ramírez, Miren Edurne; Aransay Bañares, Ana María; Abecia Aliende, Leticia; Lavín, José L.; Rodríguez López, Héctor; Anguita Castillo, Juan de Dios (Taylor and Francis, 2021-07-05)
Gut microbiota is a constant source of antigens and stimuli to which the resident immune system has developed tolerance. However, the mechanisms by which mononuclear phagocytes, specifically monocytes/macrophages, cope ...