Now showing items 1-5 of 5

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      Blood miRNA expression pattern is a possible risk marker for natalizumab-associated progressive multifocal leukoencephalopathy in multiple sclerosis patients 

      Muñoz Culla, Maider; Irizar, Haritz; Castillo Triviño, Tamara; Sáenz Cuesta, Matías; Sepúlveda, Lucía; Lopetegi, Itziar; López de Munain Arregui, Adolfo José; Olascoaga, Javier; Baranzini, Sergio; Otaegui Bichot, David (Sage, 2014-05-22)
      Background: Natalizumab has shown its efficacy in reducing multiple sclerosis (MS) relapses and progression of disability; however, it has been associated with an increased risk of developing progressive multifocal ...
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      Differential Micro RNA Expression in PBMC from Multiple Sclerosis Patients 

      Otaegui Bichot, David; Baranzini, Sergio E.; Armañanzas Arnedillo, Rubén; Calvo Molinos, Borja ORCID; Muñoz-Culla, Maider; Khankhanian, Puya; Inza Cano, Iñaki ORCID; Lozano Alonso, José Antonio; Castillo Triviño, Tamara; Asensio, Ana; Olaskoaga, Javier; López de Munain Arregui, Adolfo José (Public Library of Science, 2009-07-20)
      Differences in gene expression patterns have been documented not only in Multiple Sclerosis patients versus healthy controls but also in the relapse of the disease. Recently a new gene expression modulator has been identified: ...
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      HLA-DRB1*15:01 and multiple sclerosis: a female association? 

      Irizar, Haritz; Muñoz Culla, Maider; Zuriarrain, Olaia; Goyenechea Soto, Estibaliz; Castillo Triviño, Tamara; Prada, Alvaro; Saenz-Cuesta, Matias; De Juan, Dolores; López de Munain Arregui, Adolfo José; Olascoaga, Javier; Otaegui Bichot, David (Sage, 2011-11-29)
      Background: The association between multiple sclerosis (MS) and the HLA-DRB1*15: 01 haplotype has been proven to be strong, but its molecular basis remains unclear. Vitamin D receptor (VDR) gene variants and sex have been ...
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      Identification of ncRNAs as Potential Therapeutic Targets in Multiple Sclerosis Through Differential ncRNA – mRNA Network Analysis 

      Irizar, Haritz; Muñoz Culla, Maider; Sáenz Cuesta, Matías; Osorio Querejeta, Iñaki; Sepúlveda, Lucía; Castillo Triviño, Tamara; Prada, Alvaro; López de Munain Arregui, Adolfo José; Olascoaga, Javier; Otaegui Bichot, David (Biomed Central, 2015-03-28)
      Background: Several studies have revealed a potential role for both small nucleolar RNAs (snoRNAs) and microRNAs (miRNAs) in the physiopathology of relapsing-remitting multiple sclerosis (RRMS). This potential implication ...
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      Transcriptomic profile reveals gender-specific molecular mechanisms driving multiple sclerosis progression 

      Irizar, Haritz; Muñoz Culla, Maider; Sepúlveda, Lucía; Sáenz Cuesta, Matías; Prada, Alvaro; Castillo Triviño, Tamara; Zamora López, Gorka; López de Munain Arregui, Adolfo José; Olascoaga, Javier; Otaegui Bichot, David (Public Library Science, 2014-02-28)
      Background: Although the most common clinical presentation of multiple sclerosis (MS) is the so called Relapsing-Remitting MS (RRMS), the molecular mechanisms responsible for its progression are currently unknown. To tackle ...