Browsing by Author "Chojnacki, Jakub"

Now showing items 1-2 of 2

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      Cholesterol in the Viral Membrane is a Molecular Switch Governing HIV-1 Env Clustering 

      Nieto Garai, Jon Ander; Arboleya, Aroa; Otaegi Ugartemendia, Sara; Chojnacki, Jakub; Casas, Josefina; Fabriàs, Gemma; Contreras, F. Xabier; Kräusslich, Hans-Georg; Lorizate Nogales, Maier (Wiley, 2021-02-21)
      HIV-1 entry requires the redistribution of envelope glycoproteins (Env) into a cluster and the presence of cholesterol (chol) in the viral membrane. However, the molecular mechanisms underlying the specific role of chol ...
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      Molecular Recognition of the Native HIV-1 MPER Revealed by STED Microscopy of Single Virions 

      Carravilla Palomanes, Pablo ORCID; Chojnacki, Jakub; Rujas Díez, Edurne; Insausti González, Sara; Largo Pereda, Eneko; Waithe, Dominic; Apellaniz Unzalu, Beatriz ORCID; Sicard, Taylor; Julien, Jean Philippe; Eggeling, Christian; Nieva Escandón, José Luis (Springer, 2019-01-08)
      Antibodies against the Membrane-Proximal External Region (MPER) of the Env gp41 subunit neutralize HIV-1 with exceptional breadth and potency. Due to the lack of knowledge on the MPER native structure and accessibility, ...