Browsing by Author "Dehay, Benjamin"

Now showing items 1-2 of 2

    • Thumbnail

      CLR01 Protects Dopaminergic Neurons in Vitro and in Mouse Models of Parkinson's Disease 

      Bengoa Vergniory, Nora; Faggiani, Emilie; Ramos González, Paula; Kirkiz, Ecem; Connor-Robson, Natalie; Brown, Liam V.; Siddique, Ibrar; Li, Zizheng; Vingill, Siv; Cioroch, Milena; Cavaliere, Fabio; Threlfell, Sarah; Roberts, Bradley; Schrader, Thomas; Klaerner, Frank-Gerrit; Cragg, Stephanie; Dehay, Benjamin; Bitan, Gal; Matute Almau, Carlos José; Bezard, Erwan; Wade-Martins, Richard (Nature, 2020-09-28)
      Parkinson's disease (PD) affects millions of patients worldwide and is characterized by alpha-synuclein aggregation in dopamine neurons. Molecular tweezers have shown high potential as anti-aggregation agents targeting ...
    • Thumbnail

      Synucleinopathy alters nanoscale organization anddiffusion in the brain extracellular space throughhyaluronan remodeling 

      Soria Lannes, Federico Nicolás ORCID; Paviolo, Chiara; Doudnikoff, Evelyne; Arotcarena, Marie Laure; Lee, Antony; Danné, Noémie; Mandal, Amit Kumar; Gosset, Philippe; Dehay, Benjamin; Groc, Laurent; Cognet, Laurent; Bezard, Erwan (Nature, 2020-07-10)
      In recent years, exploration of the brain extracellular space (ECS) has made remarkable progress, including nanoscopic characterizations. However, whether ECS precise conformation is altered during brain pathology remains ...