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      Biomarkers for Dementia and Mild Cognitive Impairment in Parkinson’s Disease 

      Delgado-Alvarado, Manuel; Gago, Belén; Navalpotro-Gomez, Irene; Jiménez-Urbieta, Haritz; Rodríguez-Oroz, María C. (Movement Disorders, 2016)
      Cognitive decline is one of the most frequent and disabling nonmotor features of Parkinson's disease. Around 30% of patients with Parkinson's disease experience mild cognitive impairment, a well-established risk factor for ...
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      Disrupted salience network dynamics in Parkinson's disease patients with impulse control disorders 

      Navalpotro-Gomez, Irene; Kim, Jinhee; Paz-Alonso, Pedro M.; Delgado-Alvarado, Manuel; Quiroga-Varela, Ana; Jimenez-Urbieta, Haritz; Carreiras, Manuel; Strafella, Antonio P.; Rodriguez-Oroz, Maria Cruz (Parkinsonism and Related Disorders, 2020)
      Background: Dynamic functional network analysis may add relevant information about the temporal nature of the neurocognitive alterations in PD patients with impulse control disorders (PD-ICD). Our aim was to investigate changes ...
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      Interactions between functional networks in Parkinson's disease mild cognitive impairment 

      Delgado-Alvarado, Manuel; Ferrer-Gallardo, Vicente J.; Paz-Alonso, Pedro M.; Caballero-Gaudes, César; Rodríguez-Oroz, María C. (NATURE, 2023)
      The study of mild cognitive impairment (MCI) is critical to understand the underlying processes of cognitive decline in Parkinson’s disease (PD). Functional connectivity (FC) disruptions in PD-MCI patients have been observed ...
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      Neurogenetic traits outline vulnerability to cortical disruption in Parkinson’s disease 

      Basaia, Silvia; Agosta, Federica; Diez, Ibai; Bueichekú, Elisenda; d’Oleire Uquillas, Federico; Delgado-Alvarado, Manuel; Caballero-Gaudes, César; Rodríguez-Oroz, MariCruz; Stojkovic, Tanja; Kostic, Vladimir S.; Filippi, Massimo; Sepulcre, Jorge (Elsevier, 2022)
      The genetic traits that underlie vulnerability to neuronal damage across specific brain circuits in Parkinson’s disease (PD) remain to be elucidated. In this study, we characterized the brain topological intersection ...