Browsing by Author "Fontecha Martínez, Lara"

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      The Loss of Functional Caspase-12 in Europe Is a Pre-Neolithic Event 

      Hervella Afonso, Montserrat ORCID; Plantinga, Theo S.; Alonso Alegre, Santos ORCID; Ferwerda, Bart; Izagirre Arribalzaga, Neskuts ORCID; Fontecha Martínez, Lara; Fregel, Rosa; Van der Meer, Jos W. M.; De la Rúa Vaca, Concepción ORCID; Netea, Mihai G. (Public Library of Science, 2012-05-16)
      Background: Caspase-12 (CASP12) modulates the susceptibility to sepsis. In humans, the "C" allele at CASP12 rs497116 has been associated with an increased risk of sepsis. Instead, the derived "T" allele encodes for an ...