Melanoma is the deadliest form of skin cancer due to its ability to colonize distant sites and initiate metastasis. Although these processes largely depend on the lipid-based cell membrane scaffold, our understanding of ...

[ES] Las imágenes de masa molecular de los tejidos estarán sesgadas si las diferencias en las propiedades fisicoquímicas del microentorno afectan a la intensidad de los espectros. Para abordar esta cuestión, hemos realizado ...

Osteopontin (OPN), a multifunctional cytokine that controls liver glycerolipid metabolism, is involved in activation and proliferation of several liver cell types during regeneration, a condition of high metabolic demands. ...

Adenosine is readily available to the glandular epithelium of the stomach. Formed continuously in intracellular and extracellular locations, it is notably produced from ATP released in enteric cotransmission. Adenosine ...

Probably, the most important factor for the survival of a melanoma patient is early detection and precise diagnosis. Although in most cases these tasks are readily carried out by pathologists and dermatologists, there are ...

Osteopontin deficiency protects from obesity-related hepatosteatosis and liver fibrosis. Here we have investigated the role of osteopontin as a direct regulator of liver metabolism and whether osteopontin could be a ...

SND1 is an evolutionarily conserved multifunctional protein. Although its function has not been fully elucidated yet, is considered a multifunctional protein participating, among others, in mRNA metabolism, gene transcription ...

Background: Transcriptomic and lipidomic dual analyses usually initiate with independent extractive procedures. That entails a difficulty in aligning results from both omics platforms, especially in the case of highly ...

Although lipid droplets (LD) have traditionally been considered inert lipid deposits nowadays they are considered true organelles given their complexity and involvement in metabolism and other cellular processes. LDs ...