Listar por autor "Gómez Bilbao, Geraxane"
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Adenylate Cyclase Toxin Promotes Internalisation of Integrins and Raft Components and Decreases Macrophage Adhesion Capacity
Martín Plágaro, César Augusto; Belloso Uribe, Kepa; Gómez Bilbao, Geraxane; Ostolaza Echabe, Elena Amaya (Public Library of Science, 2011-02-23)Bordetella pertussis, the bacterium that causes whooping cough, secretes an adenylate cyclase toxin (ACT) that must be post-translationally palmitoylated in the bacterium cytosol to be active. The toxin targets phagocytes ... -
Ca2+ Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin (ACT) Endocytosis. Cell Physiology and Expression of the CD11b/CD18 Integrin Major Determinants of the Entry Route
Belloso Uribe, Kepa; Martín Plágaro, César Augusto; Etxebarria, Aitor; González Bullón, David ; Gómez Bilbao, Geraxane; Ostolaza Echabe, Elena Amaya (Public Library Publishing, 2013-09)Humans infected with Bordetella pertussis, the whooping cough bacterium, show evidences of impaired host defenses. This pathogenic bacterium produces a unique adenylate cyclase toxin (ACT) which enters human phagocytes and ...