Browsing by Author "Gaínza, Eusebio"
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iPSC-Derived Intestinal Organoids from Cystic Fibrosis Patients Acquire CFTR Activity upon TALEN-Mediated Repair of the p.F508del Mutation
Fleischer, Aarne; Vallejo Díez, Sara; Martín Fernández, José María; Sánchez Gilabert, Almudena; Castresana, Mónica; Del Pozo, Angel; Esquisabel Alegría, Amaia ; Ávila, Silvia; Castrillo, José Luis; Gaínza, Eusebio; Pedraz Muñoz, José Luis ; Viñas, Miguel; Bachiller, Daniel (Cell Press, 2020-06-12)Cystic fibrosis (CF) is the main genetic cause of death among the Caucasian population. The disease is characterized by abnormal fluid and electrolyte mobility across secretory epithelia. The first manifestations occur ...