Browsing by Author "Gurruchaga Pereda, Juan"
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Enhancing the Photocatalytic Conversion of Pt(IV) Substrates by Flavoprotein Engineering
Gurruchaga Pereda, Juan; Martínez Martínez, Virginia; Formoso Estensoro, Elena; Azpitarte Aguirre, Oxana; Rezabal Astigarraga, Elixabete; Lopez, Xabier; López Cortajarena, Aitziber
; Salassa, Luca (ACS, 2021-05-07)
Our recent work demonstrates that certain flavoproteins can catalyze the redox activation of Pt(IV) prodrug complexes under light irradiation. Herein, we used site-directed mutagenesis on the mini singlet oxygen generator ... -
Flavin-mediated bioorthogonal catalysis for drug activation.
Gurruchaga Pereda, Juan (2021-10-07)En mi tesis, he investigado la combinación de conceptos catalíticos, con las propiedades fotofísicas y fotoquímicas de las flavinas para afrontar las limitaciones de la fotoquimioterapia que emplea metales. Las modestas ...