Browsing by Author "Hayardeny, Liat"

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      Arachidyl Amido Cholanoic Acid Improves Liver Glucose and Lipid Homeostasis in Nonalcoholic Steatohepatitis Via AMPK and mTOR Regulation 

      Fernández Ramos, David; Lopitz Otsoa, Fernando; De la Cruz Villar, Laura; Bilbao García, Jon; Pagano, Martina; Mosca, Laura; Bizkarguenaga, Maider; Serrano Maciá, Marina; Azkargorta, Mikel; Iruarrizaga Lejarreta, Marta; Sot, Jesús; Tsvirkun, Darya; Van Liempd, Sebastiaan Martijn; Goñi Urcelay, Félix María ORCID; Alonso, Cristina; Martínez Chantar, María Luz ORCID; Elortza, Felix; Hayardeny, Liat; Lu, Shelly C.; Mato, José M. (Baishideng, 2020-09-14)
      BACKGROUND Arachidyl amido cholanoic acid (Aramchol) is a potent downregulator of hepatic stearoyl-CoA desaturase 1 (SCD1) protein expression that reduces liver triglycerides and fibrosis in animal models of steatohepatitis. ...
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      Metabolic subtypes of patients with NAFLD exhibit distinctive cardiovascular risk profiles 

      Martínez Arranz, Ibon; Bruzzone, Chiara; Noureddin, Mazen; Gil Redondo, Rubén; Mincholé, Itziar; Bizkarguenaga, Maider; Arretxe Oliden, Enara; Iruarrizaga Lejarreta, Marta; Fernández Ramos, David; Lopitz Otsoa, Fernando; Mayo, Rebeca; Embade, Nieves; Newberry, Elizabeth; Mittendorf, Bettina; Izquierdo Sánchez, Laura; Smid, Vaclav; Arnold, Jorge; Iruzubieta, Paula; Pérez Castaño, Ylenia; Krawczyk, Marcin; Martínez de Marigorta Izaga, Edorta ORCID; Morrison, Martine C.; Kleemann, Robert; Martín Duce, Antonio; Hayardeny, Liat; Vitek, Libor; Bruha, Radan; Aller de la Fuente, Rocio; Crespo, Javier; Romero Gómez, Manuel; Bañales Asurmendi, Jesús María ORCID; Arrese, Marco; Cusi, Kenneth; Bugianesi, Elisabetta; Klein, Samuel; Lu, Shelly C.; Anstee, Quentin M.; Millet Aguilar-Galindo, Oscar; Davidson, Nicholas O.; Alonso, Cristina; Mato, José M. (Wiley, 2022-10)
      Background and Aims We previously identified subsets of patients with NAFLD with different metabolic phenotypes. Here we align metabolomic signatures with cardiovascular disease (CVD) and genetic risk factors. Approach and ...