Browsing by Author "Kumarasinghe, Lorena"

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      P-Rex1 is a novel substrate of the E3 ubiquitin ligase Malin associated with Lafora disease 

      Kumarasinghe, Lorena; García Gimeno, María Adelaida; Ramírez Sánchez, Juan Manuel ORCID; Mayor Martínez, Ugo ORCID; Zugaza Gurruchaga, José Luis ORCID; Sanz, Pascual (Elsevier, 2023-01)
      Laforin and Malin are two proteins that are encoded by the genes EPM2A and EPM2B, respectively. Laforin is a glucan phosphatase and Malin is an E3-ubiquitin ligase, and these two proteins function as a complex. Mutations ...