Browsing by Author "Legarda, Maria"

Now showing items 1-2 of 2

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      A novel RT-QPCR-based assay for the relative quantification of residue specific m6A RNA methylation 

      Castellanos Rubio, Ainara; Santín Gómez, Izortze; Olazagoitia Garmendia, Ane; Romero Garmendia, Irati; Jauregi Miguel, Amaia; Legarda, Maria; Bilbao Catalá, José Ramón ORCID (Nature Publishing Group, 2019-12)
      N6-methyladenosine (m6A) is the most common and abundant RNA modification. Recent studies have shown its importance in the regulation of several biological processes, including the immune response, and different approaches ...
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      The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region 

      Fernández Jiménez, Nora ORCID; García Etxebarria, Koldo; Plaza Izurieta, Leticia; Romero Garmendia, Irati; Jauregi Miguel, Amaia; Legarda, Maria; Ecsedi, Szilvia; Castellanos Rubio, Ainara; Cahais, Vincent; Cuenin, Cyrille; Degli Esposti, Davide; Irastorza Terradillos, Iñaki Xarles ORCID; Hernandez-Vargas, Hector; Herceg, Zdenko; Bilbao Catalá, José Ramón ORCID (Nature Publishing, 2019-02-04)
      The Human Leucocyte Antigen (HLA) locus and other DNA sequence variants identified in Genome-Wide Association (GWA) studies explain around 50% of the heritability of celiac disease (CD). However, the pathogenesis of CD ...