Browsing by Author "Llamusí, Beatriz"

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      Preclinical characterization of antagomiR-218 as a potential treatment for myotonic dystrophy 

      Cerro Herreros, Estefanía; González Martínez, Irene; Moreno, Nerea; Espinosa Espinosa, Jorge; Fernández Costa, Juan M.; Colom Rodrigo, Anna; Overby, Sarah J.; Seoane Miraz, David; Poyatos García, Javier; Vilchez, Juan J.; López de Munain Arregui, Adolfo José; Varela, Miguel A.; Wood, Matthew J.; Pérez Alonso, Manuel; Llamusí, Beatriz; Artero, Rubén (Elsevier, 2021-12-03)
      Myotonic dystrophy type 1 (DM1) is a rare neuromuscular disease caused by expansion of unstable CTG repeats in a non-coding region of the DMPK gene. CUG expansions in mutant DMPK transcripts sequester MBNL1 proteins in ...