Browsing by Author "Ma, Tao"
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Dysregulation of the mTOR pathway mediates impairment of synaptic plasticity in a mouse model of Alzheimer's disease
Ma, Tao; Hoeffer, Charles A.; Capetillo González de Zarate, Estíbaliz ; Yu, Fangmin; Wong, Helen; Lin, Michael T.; Tampellini, Davide; Klann, Eric; Blitzer, Robert D.; Gouras, Gunnar K. (PLOS, 2010-09)Background The mammalian target of rapamycin (mTOR) is an evolutionarily conserved Ser/Thr protein kinase that plays a pivotal role in multiple fundamental biological processes, including synaptic plasticity. We explored ...