Now showing items 1-3 of 3

    • Thumbnail

      A Customized Pigmentation SNP Array Identifies a Novel SNP Associated with Melanoma Predisposition in the SLC45A2 Gene 

      Ibarrola Villava, Maider; Fernandez, Lara P.; Alonso Alegre, Santos ORCID; Boyano López, María Dolores ORCID; Peña Chilet, María; Pita, Guillermo; Avilés, José A.; Mayor, Matias; Gómez Fernández, Cristina; Casado, Beatriz; Martín González, Manuel; Izagirre Arribalzaga, Neskuts ORCID; De la Rúa Vaca, Concepción ORCID; Asumendi Mallea, Aintzane ORCID; Pérez-Yarza Pérez-Irezabal, Gorka ORCID; Arroyo Berdugo, Yoana; Boldo, Enrique; Lozoya, Rafael; Torrijos Aguilar, Arantxa; Pitarch, Ana; Pitarch, Gerard; Sánchez Motilla, José M.; Valcuende Cavero, Francisca; Tomás Cabedo, Gloria; Pérez Pastor, Gemma; Díaz Pérez, José Luis; Gardeazabal García, Jesús; Martínez de Lizarduy, Iñigo; Sánchez Díez, Ana; Valdés, Carlos; Pizarro, Angel; Casado, Mariano; Carretero, Gregorio; Botella Estrada, Rafael; Nagore, Eduardo; Lázaro, Pablo; Lluch, Ana; Benítez, Javier; Martínez Cadenas, Conrado; Ribas, Gloria (Public Library of Science, 2011-04-29)
      As the incidence of Malignant Melanoma (MM) reflects an interaction between skin colour and UV exposure, variations in genes implicated in pigmentation and tanning response to UV may be associated with susceptibility to ...
    • Thumbnail

      An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in rd10 Mice 

      Olivares González, Lorena; Velasco, Sheyla; Gallego Garrido, Idoia; Esteban Medina, Marina; Puras Ochoa, Gustavo; Loucera, Carlos; Martínez Romero, Alicia; Peña Chilet, María; Pedraz Muñoz, José Luis ORCID; Rodrigo, Regina (MDPI, 2022-12-30)
      Retinitis pigmentosa (RP) is the most common inherited retinal dystrophy causing progressive vision loss. It is accompanied by chronic and sustained inflammation, including M1 microglia activation. This study evaluated the ...
    • Thumbnail

      Sex-Specific Genetic Effects Associated with Pigmentation, Sensitivity to Sunlight, And Melanoma in a Population of Spanish Origin 

      Hernando, Barbara; Ibarrola Villava, Maider; Fernández, Lara P.; Peña Chilet, María; Llorca Cardeñosa, Marta; Oltra, Sara S.; Alonso Alegre, Santos ORCID; Boyano López, María Dolores ORCID; Martínez Cadenas, Conrado; Ribas, Gloria (Biomed Central, 2016-03-18)
      Background: Human pigmentation is a polygenic quantitative trait with high heritability. In addition to genetic factors, it has been shown that pigmentation can be modulated by oestrogens and androgens via up-or down-regulation ...