Now showing items 1-1 of 1

    • Thumbnail

      Chromosomes trapped in micronuclei are liable to segregation errors 

      Soto, Mar; García Santisteban, Iraia ORCID; Krenning, Lenno; Medema, René H.; Raaijmakers, Jonne A. (Company Biologist LTD, 2018-07-09)
      DNA in micronuclei is likely to get damaged. When shattered DNA from micronuclei gets reincorporated into the primary nucleus, aberrant rearrangements can take place, a phenomenon referred to as chromothripsis. Here, we ...