Browsing by Author "Ward, Stephen G."
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Quantification of Biomarker Functionality Predicts Patient Outcomes
Implementation of a quantitative molecular imaging method (iFRET), which determines receptor–ligand interactions, has led to the finding that patients with a low extent of PD-1/PD-L1 interaction in metastatic NSCLC, and ... -
Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma
Miles, James; Applebee, Christopher J.; Leboucher, Pierre; López Fernández, Sonia; Lee, Dae-Jin; Guarch, Rosa; Ward, Stephen G.; Parker, Peter J.; López Fernández de Villaverde, José Ignacio ; Larijani, Banafshé (Elsevier, 2017-12)Purpose: Clear cell Renal Cell Carcinomas (ccRCC), the largest group of renal tumours, are resistant to classical therapies. The determination of the functional state of actionable biomarkers for the assessment of these ...