Browsing by Author "Halim, Vincentius A."
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Doxorubicin-induced DNA Damage Causes Extensive Ubiquitination of Ribosomal Proteins Associated with a Decrease in Protein Translation
Halim, Vincentius A.; García Santisteban, Iraia ; Warmerdam, Daniel O; Van den Broek, Bram; Heck, Albert J. R.; Mohammed, Shabaz; Medema, René H. (American Society for Biochemistry and Molecular Biology, 2018-12)Protein posttranslational modifications (PTMs) play a central role in the DNA damage response. In particular, protein phosphorylation and ubiquitination have been shown to be essential in the signaling cascade that coordinates ...