BackBrowsing by Author "Hijona Muruamendiaraz, Elizabeth"
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Effect of resveratrol on alcohol-induced mortality and liver lesions in mice
Bujanda Fernández de Pierola, Luis
; García Barcina, María; Gutiérrez de Juan, Virginia; Bidaurrazaga Van Dierdonck, Joseba; Fernández de Luco, Marian; Gutiérrez Stampa, María Angeles; Larzabal, Mikel; Hijona Muruamendiaraz, Elizabeth; Sarasqueta, Cristina; Echenique Elizondo, Miguel; Arenas Mirave, Juan Ignacio (BioMed Central, 2006-11-14)
Background Resveratrol is a polyphenol with important antiinflammatory and antioxidant properties. We investigated the effect of resveratrol on alcohol-induced mortality and liver lesions in mice. Methods Mice were ... -
Evaluation of Alpha 1-Antitrypsin and the Levels of mRNA Expression of Matrix Metalloproteinase 7, Urokinase Type Plasminogen Activator Receptor and COX-2 for the Diagnosis of Colorectal Cancer
Bujanda Fernández de Pierola, Luis; ; ; ; Enríquez Navascués, José María ; ; ; ; ; ; ; (Public Library of Science, 2013-01-02)
Background: Colorectal cancer (CRC) is the second most common cause of death from cancer in both men and women in the majority of developed countries. Molecular tests of blood could potentially provide this ideal screening ... -
Genetic Variants Associated with Colorectal Adenoma Susceptibility
Abulí, Anna; Castells, Antoni; Bujanda Fernández de Pierola, Luis; Lozano, Juan José; Bessa, Xavier; Hernández, Cristina; Álvarez-Urturi, Cristina; Pellisé, María; Esteban-Jurado, Clara; Hijona Muruamendiaraz, Elizabeth; Burón, Andrea; Macià, Francesc; Grau, Jaume; Guayta, Rafael; Castellví-Bel, Sergi; Andreu, Montserrat; PROCOLON research group (PUBLIC LIBRARY SCIENCE, 2016-04-14)
Background Common low-penetrance genetic variants have been consistently associated with colorectal cancer risk. Aim To determine if these genetic variants are associated also with adenoma susceptibility and may ... -
Inflammatory Mediators of Hepatic Steatosis
Hijona Muruamendiaraz, Elizabeth; Hijona Muruamendiaraz, Lander; Arenas Mirave, Juan Ignacio; Bujanda Fernández de Pierola, Luis (Hindawi Publishing Corporation, 2010)
Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming a world-wide public health problem. NAFLD represents a spectrum of disease ranging from “simple steatosis”, which is considered relatively benign, to nonalcoholic ... -
Novel equation to determine the hepatic triglyceride concentration in humans by MRI: diagnosis and monitoring of NAFLD in obese patients before and after bariatric surgery
Jiménez Agüero, Raúl; Emparanza, José Ignacio; Beguiristain Gómez, Adolfo; Bujanda Fernández de Pierola, Luis; Alustiza Echeberria, José María; García, Elisabeth; Hijona Muruamendiaraz, Elizabeth; Gallego, Lander; Sanchez Gonzalez, Javier; Perugorria Montiel, María Jesús; Asensio, José I; Larburu Echaniz, Santiago; Garmendia Antin, Maddi ; Larzabal, Mikel; Portillo Baquedano, María Puy ; Aguirre López, Leixuri ; Bañales Asurmendi, Jesús María (Biomed Central, 2014-08-26)
Background: Non-alcoholic fatty liver disease (NAFLD) is caused by abnormal accumulation of lipids within liver cells. Its prevalence is increasing in developed countries in association with obesity, and it represents a ... -
Pravastatin inhibits cell proliferation and increased MAT1A expression in hepatocarcinoma cells and in vivo models
Hijona Muruamendiaraz, Elizabeth; Bañales Asurmendi, Jesús María; Hijona Muruamendiaraz, Lander; Medina, Juan F.; Arenas Mirave, Juan Ignacio; Herreros Villanueva, Marta; Aldazabal, Pablo; Bujanda Fernández de Pierola, Luis (BioMed Central, 2012-02-21)
Background: Statins may have therapeutic effects on hepatocarcinoma (HCC). This type of disorder is the most common malignant primary tumour in the liver. Our objective was to determine whether pravastatin had a therapeutic ... -
Pterostilbene Reduces Liver Steatosis and Modifies Hepatic Fatty Acid Profile in Obese Rats
Aguirre López, Leixuri; Palacios Ortega, Sara; Fernández Quintela, Alfredo ; Hijona Muruamendiaraz, Elizabeth; Bujanda Fernández de Pierola, Luis ; Portillo Baquedano, María Puy (MDPI, 2019-04-26)
Excessive fat accumulation within the liver is known as "simple hepatic steatosis", which is the most benign form of non-alcoholic fatty liver disease (NAFLD). The aim of the present study was to determine whether pterostilbene ... -
Resveratrol inhibits nonalcoholic fatty liver disease in rats
Bujanda Fernández de Pierola, Luis; Hijona Muruamendiaraz, Elizabeth; Larzabal, Mikel; Beraza, Marta; Aldazabal, Pablo; García Urkia, Nerea; Sarasqueta, Cristina; Cosme Jiménez, Ángel; Irastorza, Belen; González, Alberto; Arenas Mirave, Juan Ignacio (BioMed Central, 2008-09-09)
Background: The prevalence of nonalcoholic fatty liver disease (NAFLD) is high. NAFLD is linked to obesity, diabetes mellitus, and hypertriglyceridemia. Approximately 20% of patients with NAFLD will eventually develop ... -
The Dietary Antioxidant Piceatannol Inhibits Adipogenesis of Human Adipose Mesenchymal Stem Cells and Limits Glucose Transport and Lipogenic Activities in Adipocytes
; ; ; ; ; ; ; Aguirre López, Leixuri; (MDPI, 2018-07)
Phenolic compounds are among the most investigated herbal remedies, as is especially the case for resveratrol. Many reports have shown its anti-aging properties and the ability to reduce obesity and diabetes induced by ... -
TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms
Esparza Baquer, Aitor; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Andersen, Jesper B.; ; ; Bujanda Fernández de Pierola, Luis ; Bañales Asurmendi, Jesús María ; (BMJ Publishing Group, 2021-06-07)
[EN] Objective Hepatocellular carcinoma (HCC) is a prevalent and aggressive cancer usually arising on a background of chronic liver injury involving inflammatory and hepatic regenerative processes. The triggering receptor ... -
TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation
; ; ; ; ; ; Esparza Baquer, Aitor; ; ; ; ; ; ; ; ; ; ; ; ; Bujanda Fernández de Pierola, Luis ; (Elsevier, 2022-10)
Background & Aims: Inflammation, particularly that mediated by bacterial components translocating from the gut to the liver and binding to toll-like receptors (TLRs), is central to cholestatic liver injury. The triggering ...