Browsing by Author "López Cortés, Andrés"
Now showing items 1-3 of 3
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A Multi-Objective Approach for Anti-Osteosarcoma Cancer Agents Discovery through Drug Repurposing
Cabrera Andrade, Alejandro; López Cortés, Andrés; Jaramillo Koupermann, Gabriela; González Díaz, Humberto; Pazos, Alejandro; Munteanu, Cristian R.; Pérez Castillo, Yunierkis; Tejera, Eduardo (MDPI, 2020-11-22)Osteosarcoma is the most common type of primary malignant bone tumor. Although nowadays 5-year survival rates can reach up to 60–70%, acute complications and late effects of osteosarcoma therapy are two of the limiting ... -
Gene Prioritization, Communality Analysis, Networking and Metabolic Integrated Pathway to Better Understand Breast Cancer Pathogenesis
López Cortés, Andrés; Paz y Miño, César; Cabrera Andrade, Alejandro; Barigye, Stephen J.; Munteanu, Cristian R.; González Díaz, Humberto; Pazos, Alejandro; Pérez Castillo, Yunierkis; Tejera, Eduardo (Nature Publishing Group, 2018-11-12)Consensus strategy was proved to be highly efficient in the recognition of gene-disease association. Therefore, the main objective of this study was to apply theoretical approaches to explore genes and communities directly ... -
Prediction of breast cancer proteins involved in immunotherapy, metastasis, and RNA-binding using molecular descriptors and artificial neural networks
López Cortés, Andrés; Cabrera Andrade, Alejandro; Vázquez Naya, José Manuel; Pazos, Alejandro; González Díaz, Humberto; Paz y Miño, César; Guerrero, Santiago; Pérez Castillo, Yunierkis; Tejera, Eduardo; Munteanu, Cristian R. (Springer Nature, 2020-05-22)[EN] Breast cancer (BC) is a heterogeneous disease where genomic alterations, protein expression deregulation, signaling pathway alterations, hormone disruption, ethnicity and environmental determinants are involved. Due ...