BackBrowsing by Author "Naldaiz Gastesi, Neia"
Now showing items 1-6 of 6
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A neural extracellular matrix-based method for in vitro hippocampal neuron culture and dopaminergic differentiation of neural stem cells
García Parra, Patricia; Maroto, Marcos; Cavaliere, Fabio; Naldaiz Gastesi, Neia; Álava, José I.; García, Antonio G.; López de Munain Arregui, Adolfo José; Izeta Permisán, Ander
(BioMed Central, 2013)
Background: The ability to recreate an optimal cellular microenvironment is critical to understand neuronal behavior and functionality in vitro. An organized neural extracellular matrix (nECM) promotes neural cell ... -
Calcium Mechanisms in Limb-Girdle Muscular Dystrophy with CAPN3 Mutations
Lasa Elgarresta, Jaione; Mosqueira Martín, Laura; Naldaiz Gastesi, Neia; Sáenz Peña, Amets; López de Munain Arregui, Adolfo José; Vallejo Illarramendi, Ainara (MDPI, 2019-09-02)
Limb-girdle muscular dystrophy recessive 1 (LGMDR1), previously known as LGMD2A, is a rare disease caused by mutations in the CAPN3 gene. It is characterized by progressive weakness of shoulder, pelvic, and proximal limb ... -
Caracterización celular y molecular de la miogénesis dérmica de ratón y su posible traslación al humano
(2018-03-12)El estudio de la miogénesis y de diversas enfermedades neuromusculares requiere generalmente el uso de técnicas in vitro, idealmente de cultivos primarios tridimensionales.En esta tesis, se ha identificado la población de ... -
Generation of new LGMDR1 models with CRISPR/Cas9 and studies to expand insight into the disease.
(2022-11-25)La LGMDR1 es la forma más común de las distrofias musculares de cinturas, y está causada por mutaciones en el gen CAPN3. Este gen codifica la proteína calpaína 3, una proteasa no lisosomal que se expresa principalmente en ... -
Isolation and characterization of myogenic precursor cells from human cremaster muscle
Naldaiz Gastesi, Neia; Goicoechea Bianchi, María; Aragón, Isabel María; Pérez López, Virginia; Fuertes Álvarez, Sandra; Herrera Imbroda, Bernardo; López de Munain Arregui, Adolfo José; De Luna Díaz, Resi; Baptista, Pedro M.; Alejandro Fernández, M.; Lara, María Fernanda; Izeta Permisán, Ander (Nature Publishing, 2019-03-05)
Human myogenic precursor cells have been isolated and expanded from a number of skeletal muscles, but alternative donor biopsy sites must be sought after in diseases where muscle damage is widespread. Biopsy sites must be ... -
Patient-Specific iPSC-Derived Cellular Models of LGMDR1
(Elsevier, 2021-04-08)Limb-girdle muscular dystrophy recessive 1 (LGMDR1) represents one of the most common types of LGMD in the population, where patients develop a progressive muscle degeneration. The disease is caused by mutations in calpain ...