Now showing items 1-4 of 4

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      A Morphological Method for Ammonia Detection in Liver 

      Gutiérrez de Juan, Virginia; López de Davalillo, Sergio; Fernández Ramos, David; Barbier Torres, Lucía; Zubiete Franco, Imanol; Fernández Tussy, Pablo; Simón Espinosa, Jorge; Lopitz Otsoa, Fernando; De las Heras Montero, Javier Adolfo; Iruzubieta, Paula; Arias Loste, María Teresa; Villa, Erica; Crespo, Javier; Andrade, Raúl; Lucena, M. Isabel; Varela Rey, Marta; Lu, Shelly C.; Mato, José M.; Cardoso Delgado, Teresa de Jesús; Martínez Chantar, María Luz ORCID (Public Library Science, 2017-03-20)
      Hyperammonemia is a metabolic condition characterized by elevated levels of ammonia and a common event in acute liver injury/ failure and chronic liver disease. Even though hepatic ammonia levels are potential predictive ...
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      Anti-miR-518d-5p Overcomes Liver Tumor Cell Death Resistance Through Mitochondrial Activity 

      Fernández Tussy, Pablo; Rodríguez Agudo, Rubén; Fernández Ramos, David; Barbier Torres, Lucía; Zubiete Franco, Imanol; López de Davalillo, Sergio; Herráez Aguilar, Elisa; Goikoetxea Usandizaga, Naroa; Lachiondo Ortega, Sofía; Simón Espinosa, Jorge; Lopitz Otsoa, Fernando; Gutiérrez de Juan, Virginia; McCain, Misti V.; Perugorria Montiel, María Jesús; Mabe Alvarez, Jon; Navasa, Nicolás; Rodrigues, Cecilia M. P.; Fabregat, Isabel; Boix, Loreto; Sapena, Victor; Anguita Castillo, Juan de Dios; Lu, Shelly C.; Mato, José M.; Bañales Asurmendi, Jesús María ORCID; Villa, Erica; Reeves, Helen L.; Bruix, Jordi; Reig, María; Marín, José J. G.; Cardoso Delgado, Teresa de Jesús; Martínez Chantar, María Luz ORCID (Springer Nature, 2021-05-28)
      Dysregulation of miRNAs is a hallmark of cancer, modulating oncogenes, tumor suppressors, and drug responsiveness. The multi-kinase inhibitor sorafenib is one of the first-line drugs for advanced hepatocellular carcinoma ...
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      Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via DEPTOR-mTOR axis 

      Serrano Maciá, Marina; Simon, Jorge; González Rellán, María Jesús; Azkargorta, Mikel; Goikoetxea Usandizaga, Naroa; Lopitz Otsoa, Fernando; Saenz de Urturi Indart, Diego; Rodríguez Agudo, Rubén; Lachiondo Ortega, Sofía; Mercado Gómez, María; Gutiérrez de Juan, Virginia; Bizkarguenaga, Maider; Fernández Ramos, David; Buqué García, Xabier ORCID; Baselli, Guido A.; Valenti, Luca; Iruzubieta, Paula; Crespo, Javier; Villa, Erica; Bañales Asurmendi, Jesús María ORCID; Ávila, Matías A. ORCID; Marin, José J. G.; Aspichueta Celaá, Patricia; Sutherland, James D.; Barrio Olano, María Rosa; Mayor Martínez, Ugo ORCID; Elortza, Felix; Xirodimas, Dimitri; Nogueiras Pozo, Rubén; Delgado, Teresa C.; Martínez Chantar, María Luz ORCID (Elsevier, 2021-06-18)
      [EN] Objective: Neddylation is a druggable and reversible ubiquitin-like post-translational modification upregulated in many diseases, including liver fibrosis, hepatocellular carcinoma, and more recently, non-alcoholic ...
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      SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer 

      Zubiete Franco, Imanol; García-Rodríguez, Juan Luis; Lopitz Otsoa, Fernando; Serrano Maciá, Marina; Simón Espinosa, Jorge; Fernández Tussy, Pablo; Barbier Torres, Lucía; Fernández Ramos, David; Gutiérrez de Juan, Virginia; López de Davalillo, Sergio; Carlevaris, Onintza; Beguiristain Gómez, Adolfo; Villa, Erica; Calvisi, Diego; Martín Plágaro, César Augusto; Berra Ramírez, Miren Edurne; Aspichueta Celaá, Patricia; Beraza, Naiara; Varela Rey, Marta; Ávila, Matías A. ORCID; Rodríguez, Manuel S.; Mato, José M.; Díaz Moreno, Irene; Díaz Quintana, Antonio; Delgado, Teresa C.; Martínez Chantar, María Luz ORCID (Elsevier, 2019-02)
      BACKGROUND: Even though liver kinase B1 (LKB1) is usually described as a tumor suppressor in a wide variety of tissues, it has been shown that LKB1 aberrant expression is associated with bad prognosis in Hepatocellular ...