Browsing by Author "Vitallé Andrade, Joana"
Now showing items 1-13 of 13
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Altered Expression of CD300a Inhibitory Receptor on CD4+ T Cells From Human Immunodeficiency Virus-1-Infected Patients: Association With Disease Progression Markers
Vitallé Andrade, Joana; Terrén Martínez, Iñigo; Gamboa Urquijo, Leire; Orrantia Robles, Ane; Tarancón Díez, Laura; Genebat, M.; Ruíz Mateos, E.; Leal, M.; García Obregón, Susana; Zenarruzabeitia Belaustegui, Olatz; Borrego Rabasco, Francisco (Frontiers Media, 2018-07-23)The ability of the CD300a inhibitory receptor to modulate immune cell functions and its involvement in the pathogenesis of many diseases has aroused a great interest in this molecule. Within human CD4+ T lymphocytes from ... -
Arion ater barearen liseri-guruinaren karakterizazioa: hurbilketa histologikoa
Vitallé Andrade, Joana (2013-09-24)Arion ater barea, ingurumeneko kutsaduraren organismo behale moduan erabiltzen da, horregatik, baldintza normaletan liseriketan zehar liseri-guruina nola aldatzen den aztertzea interesgarria izan daiteke; izan ere, liseriketa ... -
CD300a identifies a CD4R memory T cell subset with a higher susceptibility to HIV-1 infection
Vitallé Andrade, Joana; Tarancón Díez, Laura; Jiménez León, M. R.; Terrén Martínez, Iñigo; Orrantia Robles, Ane; Roca Oporto, C.; López Cortés, L.; Ruíz Mateos, E.; Zenarruzabeitia Belaustegui, Olatz; Borrego Rabasco, Francisco (Lippincott, Williams & Wilkins, 2020-07-01)Human CD300a is known to promote the infection by dengue and other enveloped viruses and is overexpressed on CD4R T cells from HIV-1-infected patients.We found that infected CD4RRAS T cells from untreated HIV-1-infected ... -
CD300a inhibits CD16-mediated NK cell effector functions in HIV-1-infected patients
Vitallé Andrade, Joana; Terrén Martínez, Iñigo; Orrantia Robles, Ane; Pérez Garay, Raquel; Vidal, F.; Iribarren, JA; Rodríguez, C.; Lirola, A. M. L.; Bernal, E; Zenarruzabeitia Belaustegui, Olatz; Borrego Rabasco, Francisco (Springer Nature, 2019-08-29)Natural killer (NK) cell-mediated antibody-dependent cellular cytotoxicity (ADCC) through CD16 has a critical role in anti-human immunodeficiency virus (HIV) responses. CD300a, an inhibitory receptor highly expressed on ... -
CD300c costimulates IgE-mediated basophil activation, and its expression is increased in patients with cow’s milk allergy
Zenarruzabeitia Belaustegui, Olatz; Vitallé Andrade, Joana; Terrén Martínez, Iñigo; Orrantia Robles, Ane; Astigarraga Aguirre, María Icíar; Dopazo, Leire; González, Carlos; Santos Díez, Laura; Tutau Gómez, Carlos; Gamboa Setién, Pedro; Bilbao, Agurtzane; Borrego Rabasco, Francisco (Elsevier, 2019-02-05)Background: Basophils express high-affinity IgE receptors (FcεRI), which play an essential role in allergic diseases. It is important to characterize new cell-surface receptors that modulate IgE-mediated basophil activation ... -
Human CD300 receptors expression, regulation and function in the immune system. Implication in human immunodeficiency virus type 1 infection.
Vitallé Andrade, Joana (2019-12-02)Las moléculas CD300 se expresan en la superficie de células del sistema inmunitario. Estos receptores modulan numerosos procesos inmunológicos y se ha descrito que tienen un papel importante en la inmunopatogenia de distintas ... -
Human IgMhiCD300a+ B cells are circulating marginal zone memory B cells that respond to pneumococcal polysaccharides and their frequency is decreased in people living with HIV
Zenarruzabeitia Belaustegui, Olatz; Vitallé Andrade, Joana; Merino Pérez, Aitana; Terrén Martínez, Iñigo; Orrantia Robles, Ane; Pacho de Lucas, Arantza; Iribarren Loyarte, José Antonio; García Fraile, Lucio; Balsalobre, Luz; Amo Herrero, Laura; De Andrés, Belén; Borrego Rabasco, Francisco (MDPI, 2023-09-06)CD300a is differentially expressed among B cell subsets, although its expression on IgM+ B cells is not well known. We have identified a B cell subset expressing CD300a and high levels of IgM (IgMhiCD300a+). Results showed ... -
Implication of Interleukin-12/15/18 and Ruxolitinib in the Phenotype, Proliferation, and Polyfunctionality of Human Cytokine-Preactivated Natural Killer Cells
Terrén Martínez, Iñigo; Mikelez Alonso, Idoia; Odriozola, Irati; Gredilla, Andrea; González, Javier; Orrantia Robles, Ane; Vitallé Andrade, Joana; Zenarruzabeitia Belaustegui, Olatz; Borrego Rabasco, Francisco (Frontiers Media, 2018-04-16)A brief in vitro stimulation of natural killer (NK) cells with interleukin (IL)-12, IL-15, and IL-18 endow them a memory-like behavior, characterized by higher effector responses when they are restimulated after a resting ... -
Increased expression levels of CD300c on basophils from allergic individuals
Vitallé Andrade, Joana; Terrén Martínez, Iñigo; Orrantia Robles, Ane; Segurola, Aritza; Seras, Yolanda; Gamboa Setién, Pedro; Borrego Rabasco, Francisco; Zenarruzabeitia Belaustegui, Olatz (World Allergy Organization Journal, 2019-09-30)CD300c is a co-stimulatory receptor for IgE-mediated signals on human basophils. Basophils from allergic individuals exhibit higher expression levels of CD300c. This receptor could serve as a potential therapeutic target ... -
Metabolic changes of Interleukin‑12/15/18‑stimulated human NK cells
Terrén Martínez, Iñigo; Orrantia Robles, Ane; Mosteiro Couso, Alba; Vitallé Andrade, Joana; Zenarruzabeitia Belaustegui, Olatz; Borrego Rabasco, Francisco (Nature, 2021-03-19)Natural Killer (NK) cells acquire memory-like properties following a brief stimulation with IL-12, IL-15 and IL-18. These IL-12/15/18-preactivated NK cells, also known as cytokine-induced memorylike (CIML) NK cells, have ... -
Monocytes Phenotype and cytokine Production in human immunodeficiency Virus-1 infected Patients receiving a Modified Vaccinia ankara-Based hiV-1 Vaccine: relationship to cD300 Molecules expression
Vitallé Andrade, Joana; Zenarruzabeitia Belaustegui, Olatz; Terrén Martínez, Iñigo; Plana, M.; Guardo, A. C.; Leal, L.; Peña, J.; García, F.; Borrego Rabasco, Francisco (Frontiers Media, 2017-07-21)A modified vaccinia Ankara-based HIV-1 vaccine clade B (MVA-B) has been tested for safety and immunogenicity in low-risk human immunodeficiency virus (HIV)-uninfected individuals and as a therapeutic vaccine in HIV-1-infected ... -
Polyfunctional HIV-1 specific response by CD8+ T lymphocytes expressing high levels of CD300a
Vitallé Andrade, Joana; Terrén Martínez, Iñigo; Gamboa Urquijo, Leire; Orrantia Robles, Ane; Tarancón Díez, Laura; Genebat, M.; Leal, M.; Ruíz Mateos, E.; Borrego Rabasco, Francisco; Zenarruzabeitia Belaustegui, Olatz (Springer Nature, 2020-04-08)CD300a receptor is found on different CD8+ T cell subsets and its expression has been associated to a more cytotoxic molecular signature. CD300a has an important role in some viral infections and its expression levels ... -
The expression and function of human CD300 receptors on blood circulating mononuclear cells are distinct in neonates and adults
Zenarruzabeitia Belaustegui, Olatz; Vitallé Andrade, Joana; García Obregón, Susana; Astigarraga Aguirre, María Icíar; Astigarraga Aguirre, María Iciar; Eguizabal Argaiz, Cristina ; Santos, Silvia; Simhadri, V. R.; Borrego Rabasco, Francisco (Nature Research, 2016-09-06)Neonates are more susceptible to infections than adults. This susceptibility is thought to reflect neonates’ qualitative and quantitative defects in the adaptive and innate immune responses. Differential expression of cell ...