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Osteopontin: a key regulator of liver lipid metabolism
(2016-04-25)
Osteopontin deficiency protects from obesity-related hepatosteatosis and liver fibrosis. Here we have investigated the role of osteopontin as a direct regulator of liver metabolism and whether osteopontin could be a ...
Role of SOX17 in the regulation of the biliary phenotype and in cholangiocarcinogenesis
(2016-03-07)
El colangiocarcinoma (CCA) es un grupo heterogéneo de cánceres que afecta a las células de los conductos biliares (i.e. colangiocitos) y que presenta elevada letalidad debido a su diagnóstico tardío y quimioresistencia. ...
Antitumoral actions of Vismia baccifera on human hepatocellular carcinoma HepG2
(2016-07-26)
Nowadays there is an increasing interest in finding bioactive compounds which can be used as chemopreventive agents against cancer. In this work, we have studied the antitumoral actions of aqueous extracts from leaves of ...