Browsing TD-Ciencias by Author "Reichardt, Niels Christian"
Now showing items 1-5 of 5
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Chemoenzymatic synthesis and immunological studies of Xylosylated N-glycans
Brzezicka, Katarzyna Alicja (2016-06-07)Glycosylation is one of the most common post-translational modifications in eukaryotic cells. It changes during cell development and differentiation and it is tissue and more importantly, species specific. While core ¿-1,6 ... -
NMR studies of the interactions of glycan antigens with monoclonal antibodies.
Calloni, Ilaria (2020-06-29)Carbohydrates are one of the most variable and complex molecules of biological systems. They are usually located at the cell membrane, mainly as glycoconjugates, glycoproteins or glycolipids and play an important role in ... -
Solid-phase synthesis of glicosaminoglycans
Guedes Carrerra, Nerea (2017-09-15)Glycosaminoglycans (GAGs) are highly charged and linear polysaccharide repeating units (with the exception of keratin sulfate), which are further classified according their monosaccharide composition and glycosidic linkage. ... -
Synthesis Of N-glycan mimetics and their evaluation as C-type lectin receptor (Clr) antagonists using microarray technology
Cioce, Anna (2019-02-01)Carbohydrate microarrays are well established tools for high-throughput analysis of carbohydrate-protein interactions and for screening the specificity of carbohydrate processing enzymes, In addition, a few groups have ... -
Synthesis, screening and use of parasitic O-glycans and mimetics for improved C-type lectin receptor targeting
Pham, Julie Thanh (2018-11-24)O-glycans from the helminth Schistosoma mansoni represent promising leads in the development of immunomodulatory compounds via the interaction with C-type lectin receptors (CLRs), as reported for DC-SIGN, L-SIGN, Langerin ...