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Oligodendrocyte differentiation from adult multipotent stem cells is modulated by glutamate

Cavaliere, Fabio; Urra, O.; Alberdi Alfonso, Elena María; Matute Almau, Carlos José (Nature Publishing Group, 2012-02)

We used multipotent stem cells (MSCs) derived from the young rat subventricular zone (SVZ) to study the effects of glutamate in oligodendrocyte maturation. Glutamate stimulated oligodendrocyte differentiation from SVZ-derived ...

1-42 beta-Amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death

Manterola, L.; Hernando Rodríguez, M.; Ruiz Núñez, Asier; Apraiz, A.; Arrizabalaga, O.; Vellon, L.; Alberdi Alfonso, Elena María; Cavaliere, Fabio; Lacerda, H. M.; Jimenez, S.; Parada, L. A.; Matute Almau, Carlos José; Zugaza Gurruchaga, José Luis (Nature Publishing Group, 2013-01)

1-42 beta-Amyloid (A beta(1-42)) peptide is a key molecule involved in the development of Alzheimer's disease. Some of its effects are manifested at the neuronal morphological level. These morphological changes involve ...