Sistema endokannabinoideak emearen ugal-fisiologia modulatzen du
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Date
2022Author
Olabarrieta Lopez, Estibaliz
Aguirregoitia Marcos, Ekaitz
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Ekaia 42 : 241-252 (2022)
Abstract
Sistema kannabinideak ugal-sistemaren prozesu desberdinetan parte hartzen du, eta jakina da kannabinoide exogenoen kontsumo kroniko sistemikoa kaltegarria dela ugalketa-prozesuetarako; sistema endokannabinoidean izan daitezkeen gabeziak, halaber, ez dira mesedegarriak. Frogatu da sistema endokannabinoidearen edozein osagairen aktibazioak edo eraldaketek eragina izan dezaketela ugalketaren fase desberdinen erregulazioan eta bizitza berri baten hasiera arriskuan jar dezaketela. Horregatik, kannabinoideen erabilera lagungarria izan liteke, antzutasunaren diagnostikoan biomarkatzaile posible gisa edota praktika klinikoan tratatzeko itu terapeutiko posible bezala.; The cannabinoid system is involved in many aspects of reproduction and it is known that the systemic chronic use of exogenous CBs is deleterious to reproductive processes. However, possible deficiencies in the endocannabinoid system are also harmful. Therefore, both CB under and overexposure could affect the regulation of the different phases of reproduction and endanger the start of a new life. Hence, the use of cannabinoids as a possible biomarker in the diagnosis of sterility or as a possible therapeutic target in clinical practice has begun to be studied.