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dc.contributor.advisorOrio, Patricio
dc.contributor.advisorCortes Díaz, Jesús María
dc.contributor.authorGatica Briceño, Marilyn Marjorie
dc.description82 p.es_ES
dc.description.abstractThe human brain generates a large repertoire of spatio-temporal patterns, which supporta wide variety of motor, cognitive, and behavioral functions. The most acceptedhypothesis in modern neuroscience is that each of these representations is encoded indifferent brain networks. From MRI, networks can be defined anatomically (¿structuralconnectivity¿-SC) or functionally (¿functional connectivity¿-FC). Interestingly, while SCis by definition pairwise (white matter fibers project from one region to another), FC isnot. In this thesis we have focused on the study of high-order interactions (HOI) that occur in functional networks, beyond the existing statistical relationships in pairs of regions.When evaluating the interacting n-plets, from triplets to order n, a novel type of statistical interdependencies appear, namely the synergistic and redundant interactions,which are inaccessible when evaluating interacting pairs. The study of these HOI inthe human brain in aging and neurodegeneration is the purpose of this thesis.es_ES
dc.description.sponsorshipBiocruces Bizkaiaes_ES
dc.subjectdata analysises_ES
dc.subjectanálisis de datoses_ES
dc.titleAdvances of high-order interactions in the human brain: Applications in aging and neurodegeneration.es_ES
dc.rights.holderAtribución-NoComercial 3.0 España*
dc.rights.holder(cc)2022 MARILYN MARJORIE GATICA BRICEÑO (cc by-nc 4.0)
dc.departamentoesBiología celular e histologíaes_ES
dc.departamentoeuZelulen biologia eta histologiaes_ES

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Atribución-NoComercial 3.0 España
Except where otherwise noted, this item's license is described as Atribución-NoComercial 3.0 España