Browsing INVESTIGACIÓN by Author "Valcárcel-Martín, Roberto"
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Lysophosphatidic acid receptor 1 labels seizure-induced hippocampal reactive neural stem cells and controls their activation.
En la regulación de la neurogénesis hipocampal adulta, un paso fundamental es la división de las células madre neurales (NSCs) ya que, tras activarse, se dividen varias veces consecutivas y se diferencian después en ... -
Lysophosphatidic Acid Receptor 1 Specifically Labels Seizure-Induced Hippocampal Reactive Neural Stem Cells and Regulates Their Division
Valcárcel Martín, Roberto ; Martín Suárez, Soraya; Muro García, Teresa; Pastor Alonso, Oier; Rodríguez de Fonseca, Fernando; Estivill Torrús, Guillermo; Encinas Pérez, Juan Manuel (Frontiers Media, 2020-08-14)A population of neural stem cells (NSCs) dwelling in the dentate gyrus (DG) is able to generate neurons throughout adult life in the hippocampus of most mammals. These NSCs generate also astrocytes naturally and are capable ... -
Reactive Disruption of the Hippocampal Neurogenic Niche After Induction of Seizures by Injection of Kainic Acid in the Amygdala
Muro García, Teresa; Martín Suárez, Soraya; Espinosa, Nelson; Valcárcel Martín, Roberto ; Marinas, Ainhoa; Zaldumbide Dueñas, Laura; Galbarriatu, Lara; Sierra Saavedra, Amanda; Fuentealba, Pablo; Encinas Pérez, Juan Manuel (Frontiers Media, 2019-08-20)Adult neurogenesis persists in the adult hippocampus due to the presence of multipotent neural stem cells (NSCs). Hippocampal neurogenesis is involved in a range of cognitive functions and is tightly regulated by neuronal ...