Browsing INVESTIGACIÓN by Author "Caballero Cuenca, Unai"
Now showing items 1-5 of 5
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In Vitro Interaction and Killing-Kinetics of Amphotericin B Combined with Anidulafungin or Caspofungin against Candida auris
Caballero Cuenca, Unai; Eraso Barrio, María Elena ; Quindós Andrés, Guillermo; Jauregizar Albonigamayor, Nerea (MDPI, 2021-08-25)Treatment of invasive infections caused by Candida auris is challenging due to the limited therapeutic options. The combination of antifungal drugs may be an interesting and feasible approach to be investigated. The aim ... -
In Vitro Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Amphotericin B against Candida auris
Caballero Cuenca, Unai; Eraso Barrio, María Elena ; Pemán, Javier; Quindós Andrés, Guillermo; Vozmediano, Valvanera; Schmidt, Stephan; Jauregizar Albonigamayor, Nerea (MDPI, 2021-10-22)The aims of this study were to characterize the antifungal activity of amphotericin B against Candida auris in a static in vitro system and to evaluate different dosing schedules and MIC scenarios by means of semi-mechanistic ... -
In Vitro Synergistic Interactions of Isavuconazole and Echinocandins against Candida auris
Caballero Cuenca, Unai; Kim, Sarah; Eraso Barrio, María Elena ; Quindós Andrés, Guillermo; Vozmediano, Valvanera; Schmidt, Stephan; Jauregizar Albonigamayor, Nerea (MDPI, 2021-03-28)Candida auris is an emergent fungal pathogen that causes severe infectious outbreaks globally. The public health concern when dealing with this pathogen is mainly due to reduced susceptibility to current antifungal drugs. ... -
Pharmacometric analysis of the in vitro activity of echinocandins, amphotericin B and isavuconazole against Candida Auris
Caballero Cuenca, Unai (2021-07-19)C. auris is a multidrug-resistant fungal pathogen that has recently emerged globally as a cause of life-threatening invasive infections. Despite the increasing concern on the reduced treatment options of C. auris infections, ... -
PK/PD modeling and simulation of the in vitro activity of the combinations of isavuconazole with echinocandins against Candida auris
Caballero Cuenca, Unai; Eraso Barrio, María Elena ; Quindós Andrés, Guillermo; Vozmediano, Valvanera; Schmidt, Stephan; Jauregizar Albonigamayor, Nerea (Wiley, 2023-06)In vitro combination of echinocandins and isavuconazole against the emerging species Candida auris is mainly synergistic. However, this combination has not been evaluated in clinical settings. A pharmacokinetic/pharmacodynamic ...